Ku Ja Hyeon, Yeo Woon Geol, Han Deok Hyeon, Lee Sung Won, Kim Hyeon Hoe
Department of Urology, Seoul National University College of Medicine, Seoul, Korea.
Int J Urol. 2005 May;12(5):436-41. doi: 10.1111/j.1442-2042.2005.01086.x.
We compared the results of hand-assisted laparoscopic living donor nephrectomy (LLDN) and conventional open living donor nephrectomy (OLDN).
The clinical data on 49 hand-assisted LLDN and 21 OLDN on the left side performed at two institutions in Korea from January 2001 to February 2003 were reviewed. Demographic data of donors and recipients were similar in the two groups.
There was one conversion to an open procedure due to bleeding in the LLDN group. The median operation times (180 min in LLDN versus 170 min in OLDN) and warm ischemic times (2.5 min in LLDN versus 2.0 min in OLDN) in the two groups were similar. The estimated mean blood loss, duration of hospital stay and complication rate was also similar in the two groups. The LLDN group reported less pain (visual analog scale) postoperatively (4.1 versus 5.3), but this was not significant (P=0.058). The time to oral intake in the LLDN group was significantly longer by an average of 1 day (P=0.001). Return to work was sooner in the LLDN group (4.0 weeks versus 6.0 weeks; P=0.026). The recipient graft function was equivalent between the two groups. Hand-assisted LLDN appears to be a safe and effective alternative to OLDN.
Our findings suggest that this technique may give the ability provide grafts of similar quality to OLDN, while extending to the donors the advantages of a traditional LLDN procedure.
我们比较了手辅助腹腔镜活体供肾切除术(LLDN)和传统开放性活体供肾切除术(OLDN)的结果。
回顾了2001年1月至2003年2月在韩国两家机构进行的49例手辅助LLDN和21例左侧OLDN的临床资料。两组供体和受体的人口统计学数据相似。
LLDN组中有1例因出血转为开放手术。两组的中位手术时间(LLDN为180分钟,OLDN为170分钟)和热缺血时间(LLDN为2.5分钟,OLDN为2.0分钟)相似。两组的估计平均失血量、住院时间和并发症发生率也相似。LLDN组术后疼痛(视觉模拟评分)较轻(4.1对5.3),但差异无统计学意义(P=0.058)。LLDN组开始经口进食的时间平均显著延长1天(P=0.001)。LLDN组恢复工作的时间更早(4.0周对6.0周;P=0.026)。两组受体的移植肾功能相当。手辅助LLDN似乎是OLDN的一种安全有效的替代方法。
我们的研究结果表明,该技术可能能够提供与OLDN质量相似的移植物,同时为供体带来传统LLDN手术的优势。