并非所有的自噬膜都是平等的。
Not all autophagy membranes are created equal.
机构信息
Frankfurt Institute for Molecular Life Sciences, Goethe University School of Medicine, Theodor-Stern-Kai 7, D-60590 Frankfurt am Main, Germany.
出版信息
Cell. 2010 May 14;141(4):564-6. doi: 10.1016/j.cell.2010.04.030.
PMID:20478247
Abstract
During starvation, the cell recycles cytoplasmic material by sequestering it in double-membrane organelles, called autophagosomes, which eventually fuse with lysosomes. In this issue, Hailey et al. (2010) identify the outer membrane of mitochondria as a new source of autophagosomal membranes during starvation.
摘要
在饥饿状态下，细胞通过将细胞质物质隔离在称为自噬体的双层膜细胞器中来回收细胞质物质，自噬体最终与溶酶体融合。在本期杂志中，Hailey 等人（2010）确定了线粒体的外膜是饥饿状态下自噬体膜的一个新来源。
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