Case Western Reserve School of Dental Medicine, Cleveland, Ohio 44106, USA.
J Endod. 2010 Jun;36(6):974-7. doi: 10.1016/j.joen.2010.03.027. Epub 2010 Apr 24.
More than 1 million total joint replacements, mostly hip and knee, are performed each year in the United States, and the number is increasing. The American Academy of Orthopedic Surgeons has issued a new information statement that dramatically changes the need for premedication with antibiotics before dental appointments.
The prior advisory statements, jointly released in 1997 and 2003 by the American Dental Association and American Academy of Orthopedic Surgeons, recommended premedication for only 2 years after the surgical placement of the implant(s) for patients undergoing total arthroplasty and/or for immune-compromised patients. The current information statement indicates that those patients with total joint replacement should be premedicated for any dental procedure with a risk of causing bacteremia for the lifetime of the patient.
There is no well-documented, convincing published evidence with modern molecular methods of species identification in which the reported species was specific to a dental procedure in the orofacial region to the subsequently infected total joint replacement.
Further discussions between orthopedic surgeons, general medical practitioners, and dental practitioners should be encouraged to reach a mutual consensus on this controversial issue to provide the best protection for patients receiving dental treatment potentially resulting in transient bacteremia. Moreover, difficult randomized controlled trials must be conducted to determine the best treatment to minimize infections of total joint replacements and reduce morbidity and mortality.
每年在美国有超过 100 万例全关节置换术(主要是髋关节和膝关节置换术),而且这个数字还在不断增加。美国骨科医师学会发布了一项新的信息声明,该声明极大地改变了在进行牙科预约前进行抗生素预用药的需求。
1997 年和 2003 年,美国牙科协会和美国骨科医师学会联合发布了先前的咨询声明,仅建议在植入物(s)手术后的 2 年内对接受全关节置换术和/或免疫功能低下的患者进行预用药。目前的信息声明指出,对于那些接受全关节置换术的患者,任何有引起菌血症风险的牙科手术都应进行终生预用药。
目前尚无现代分子方法进行物种鉴定的记录在案的、令人信服的出版证据表明,报告的物种是特定于口腔区域的牙科手术,随后感染了全关节置换术。
应鼓励骨科医生、普通内科医生和牙科医生之间进一步讨论,以就这一有争议的问题达成共识,为接受潜在引起短暂菌血症的牙科治疗的患者提供最佳保护。此外,必须进行困难的随机对照试验,以确定最佳治疗方法,以最大限度地减少全关节置换感染,降低发病率和死亡率。