Nguyen-Khac Florence
Unite de Cytogénétique Hématologique, Service d'Hématologie Biologique, Groupe Hospitalier de la Pitié-Salpêtrière, Paris.
Ann Biol Clin (Paris). 2010 May-Jun;68(3):273-6. doi: 10.1684/abc.2010.0443.
Recurrent cytogenetic abnormalities observed in chronic lymphocytic leukaemia (CLL) are frequent. They involve the 13q, 11q, 12q, 17p and 6q chromosomal regions, by decreasing order of frequency. These abnormalities can be isolated or associated. They can also appear during the course of the disease. Some of them, as 11q and 17p deletions, give prognostic information for the management of CLL patients.
