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人类神经科学与衰老的心智:旧问题的新视角。

Human neuroscience and the aging mind: a new look at old problems.

机构信息

Department of Psychology, University of Michigan, Ann Arbor, MI 48109, USA.

出版信息

J Gerontol B Psychol Sci Soc Sci. 2010 Jul;65(4):405-15. doi: 10.1093/geronb/gbq035. Epub 2010 May 17.

DOI:10.1093/geronb/gbq035
PMID:20478901
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2883872/
Abstract

In this article, marking the 65th anniversary of the Journal of Gerontology, we offer a broad-brush overview of the new synthesis between neuroscientific and psychological approaches to cognitive aging. We provide a selective review of brain imaging studies and their relevance to mechanisms of cognitive aging first identified primarily from behavioral measurements. We also examine some new key discoveries, including evidence favoring plasticity and compensation that have emerged specifically from using cognitive neuroscience methods to study healthy aging. We then summarize several recent neurocognitive theories of aging, including our own model-the Scaffolding Theory of Aging and Cognition. We close by discussing some newly emerging trends and future research trajectories for investigating the aging mind and brain.

摘要

在这篇文章中,标志着《老年学期刊》创刊 65 周年,我们提供了神经科学和心理学方法对认知老化的新综合的广泛概述。我们选择性地回顾了脑成像研究及其与主要通过行为测量确定的认知老化机制的相关性。我们还检查了一些新的关键发现,包括从使用认知神经科学方法研究健康衰老中出现的支持可塑性和补偿的证据。然后,我们总结了几个最近的神经认知衰老理论,包括我们自己的模型——衰老和认知的支架理论。最后,我们讨论了一些新出现的趋势和未来的研究轨迹,用于研究衰老的心智和大脑。

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Cognitive activities delay onset of memory decline in persons who develop dementia.认知活动可延缓患痴呆症者记忆力衰退的 onset(此处“onset”结合语境推测为“开始”之意,整句意思是延缓记忆力衰退的开始,即延缓衰退的进程)。
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