表皮脂质、屏障功能与脱屑
Epidermal lipids, barrier function, and desquamation.
作者信息
Elias P M
机构信息
Dermatology Service, Veterans Administration Medical Center, and Department of Dermatology, University of California School of Medicine, San Francisco, California, U.S.A.
出版信息
J Invest Dermatol. 1983 Jun;80(1 Suppl):44s-9s. doi: 10.1038/jid.1983.12.
PMID:20479733
Abstract
Based on recent morphologic, histochemical, and biochemical data, we propose a heterogeneous two-compartment model of the stratum corneum that ascribes a special role for intercellular lipids in the regulation of stratum corneum barrier function and desquamation. The evidence in favor of the model and several predictions based on the model are surveyed in this review.
摘要
基于最近的形态学、组织化学和生物化学数据，我们提出了一种角质层的异质双室模型，该模型认为细胞间脂质在角质层屏障功能调节和脱屑过程中发挥特殊作用。本综述探讨了支持该模型的证据以及基于该模型的若干预测。
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