National Eye Institute, National Institutes of Health, Bethesda, Maryland, USA.
Ocul Immunol Inflamm. 2010 Jun;18(3):181-3. doi: 10.3109/09273941003728947.
To describe a case of orbital mucosa-associated lymphoid tissue (MALT) lymphoma masquerading as unilateral panuveitis.
Retrospective chart review.
A 53-year-old female patient with unilateral vitritis and exudative retinal detachment refractory to immunosuppressive treatment was eventually diagnosed with orbital MALT lymphoma. Following treatment with radiotherapy and rituximab, the patient's intraocular inflammation and retinal detachment resolved.
Orbital MALT lymphoma can masquerade as refractory unilateral panuveitis with exudative retinal detachment and appears to respond to a combination of radiotherapy and specific B-cell-targeted systemic therapy.
描述一例以单侧全葡萄膜炎为表现的眼眶黏膜相关淋巴组织(MALT)淋巴瘤。
回顾性病历分析。
一例 53 岁女性患者,以单侧眼葡萄膜炎伴渗出性视网膜脱离为表现,对免疫抑制治疗无反应,最终诊断为眼眶 MALT 淋巴瘤。接受放射治疗和利妥昔单抗治疗后,患者眼内炎症和视网膜脱离得到缓解。
眼眶 MALT 淋巴瘤可表现为对抗生素治疗无效的单侧全葡萄膜炎伴渗出性视网膜脱离,似乎对放射治疗联合特定 B 细胞靶向全身治疗有效。