Suppr超能文献

[胃旁路手术对病态肥胖有效]

[Gastric bypass surgery effective for morbid obesity].

作者信息

van Doesburg Ingrid A J, te Riele Wouter W, Boerma Djamila, Eland Ingo A, Wiezer M J René, van Ramshorst Bert

机构信息

St. Antonius Ziekenhuis, Afd. Chirurgie, Nieuwegein, The Netherlands.

出版信息

Ned Tijdschr Geneeskd. 2010;154:A1138.

Abstract

OBJECTIVE

Evaluation of the results of Roux-en-Y gastric bypass in morbid obesity.

DESIGN

Descriptive.

METHODS

All patients undergoing gastric bypass surgery in St. Antonius Hospital in Nieuwegein, the Netherlands, between 2002 and 2008 were analysed. Indications were a body mass index (BMI) >or= 40 kg/m2 or a BMI >or= 35 kg/m2 with severe co-morbidity. Principal outcomes were excess weight loss after at least 1 year of follow-up, surgery-related morbidity and mortality.

RESULTS

290 patients with a median age of 42.5 years (range: 21-66) underwent gastric bypass surgery (open: n = 233, laparoscopic: n = 57). The median preoperative overweight above standard weight was 78.7 kg (range: 30.1-190.3) and the median BMI was 49.5 kg/m2 (range: 33.2-84.9). This concerned a secondary intervention after a previous unsuccessful bariatric procedure in 99/290 patients (34.1%). There were 189 patients with a follow-up of more than 1 year. The procedure was successful (>or= 50% excess weight loss) in 135/189 patients (71.4%). The median excess weight loss was 58.6% (range: 7.7-102.4). The BMI decreased by a median of 16.2 kg/m(2) (range: 0.9-42.9). Patients undergoing primary surgery lost a higher percentage of excess weight than patients undergoing secondary surgery (median percentage excess weight loss 61.4% versus 53.5% , and a median decrease in BMI of 17.8 versus 11.9 kg/m2). The most frequently occurring early complications (within 30 days of surgery) were anastomotic leak (n = 15) and wound infection (n = 11). Late complications included anastomotic stricture (n = 18) and cicatricial hernia (n = 15). Mortality was 0.7% (n = 2).

CONCLUSION

Gastric bypass surgery was an effective treatment strategy for morbid obesity and had acceptable surgery-related morbidity and mortality.

摘要

目的

评估Roux-en-Y胃旁路手术治疗病态肥胖症的效果。

设计

描述性研究。

方法

对2002年至2008年期间在荷兰新韦根圣安东尼医院接受胃旁路手术的所有患者进行分析。手术指征为体重指数(BMI)≥40 kg/m²或BMI≥35 kg/m²且伴有严重合并症。主要结局指标为至少随访1年后的超重减轻情况、手术相关的发病率和死亡率。

结果

290例患者接受了胃旁路手术,中位年龄为42.5岁(范围:21 - 66岁)(开放手术:n = 233,腹腔镜手术:n = 57)。术前高于标准体重的超重中位数为78.7 kg(范围:30.1 - 190.3),BMI中位数为49.5 kg/m²(范围:33.2 - 84.9)。在99/290例患者(34.1%)中,这是在先前减肥手术失败后的二次干预。有189例患者随访超过1年。该手术在135/189例患者(71.4%)中成功(超重减轻≥50%)。超重减轻的中位数为58.6%(范围:7.7 - 102.4)。BMI中位数下降了16.2 kg/m²(范围:0.9 - 42.9)。接受初次手术的患者超重减轻的百分比高于接受二次手术的患者(超重减轻的中位数百分比分别为61.4%和53.5%,BMI中位数下降分别为17.8和11.9 kg/m²)。最常见的早期并发症(术后30天内)是吻合口漏(n = 15)和伤口感染(n = 11)。晚期并发症包括吻合口狭窄(n = 18)和瘢痕性疝(n = 15)。死亡率为0.7%(n = 2)。

结论

胃旁路手术是治疗病态肥胖症的有效治疗策略,且手术相关的发病率和死亡率可接受。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验