Wang Y A, Zheng J W, Zhu H G, Ye W M, He Y, Zhang Z Y
Department of Oral and Maxillofacial Surgery, College of Stomatology, Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, No. 639, Zhi Zao Ju Road, Shanghai 200011, PR China.
Phlebology. 2010 Jun;25(3):138-44. doi: 10.1258/phleb.2009.009019.
Venous malformation (VM) is the most common symptomatic low-flow vascular malformation, which predominantly occurs in the head and neck region. The aim of this paper was to evaluate the results of endovascular sclerotherapy of voluminous VM, when the lesion is either >or=15 cm in maximum diameter or the lesion invades more than one anatomical space, in the head and neck region using absolute ethanol under digital subtraction angiography (DSA) guidance.
A total of 23 patients with head and neck VMs between October 2005 and December 2008 were retrospectively reviewed. All patients received direct puncture ethanol sclerotherapy under DSA guidance. Follow-up assessments were performed at 3-25 months after therapies were completed, and complications were reported in some cases.
All patients were satisfied with the results of therapy. Seventeen patients (73.9%) achieved excellent responses and six patients (26.1%) achieved good responses in magnetic resonance imaging assessments. Minor complications developed during the procedures, all of which were successfully managed with full recovery during follow-ups. Serious complications such as acute pulmonary hypertension, cardiovascular collapse and pulmonary embolism were not encountered.
It is concluded that sclerotherapy with absolute ethanol under DSA guidance is an important alternative therapy for voluminous and extensive VM, as the procedure is reasonably safe and offers good therapeutic results.
静脉畸形(VM)是最常见的有症状的低流量血管畸形,主要发生在头颈部区域。本文的目的是评估在数字减影血管造影(DSA)引导下,使用无水乙醇对最大直径≥15 cm或病变侵犯头颈部一个以上解剖间隙的巨大VM进行血管内硬化治疗的效果。
回顾性分析2005年10月至2008年12月期间共23例头颈部VM患者。所有患者均在DSA引导下接受直接穿刺无水乙醇硬化治疗。治疗完成后3 - 25个月进行随访评估,部分病例报告了并发症。
所有患者对治疗结果满意。在磁共振成像评估中,17例患者(73.9%)取得了优异的反应,6例患者(26.1%)取得了良好的反应。术中出现了轻微并发症,所有这些并发症在随访期间均得到成功处理并完全恢复。未遇到急性肺动脉高压、心血管虚脱和肺栓塞等严重并发症。
得出结论,在DSA引导下使用无水乙醇进行硬化治疗是治疗巨大且广泛VM的一种重要替代疗法,因为该操作相当安全且疗效良好。