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面部和颈部静脉畸形的无水乙醇硬化治疗

Absolute ethanol sclerotherapy for venous malformations in the face and neck.

作者信息

Su Lixin, Fan Xindong, Zheng Lianzhou, Zheng Jiawei

机构信息

Department of Oral and Maxillofacial Surgery, Shangai Second Medical University, Shanghai, People's Republic of China.

出版信息

J Oral Maxillofac Surg. 2010 Jul;68(7):1622-7. doi: 10.1016/j.joms.2009.07.094. Epub 2009 Dec 4.

Abstract

PURPOSE

The purpose of the present study was to evaluate the outcomes of sclerotherapy using absolute ethanol for venous malformations in the face and neck.

PATIENTS AND METHODS

We treated 60 consecutive patients with venous malformations in the face and neck with sclerotherapy with absolute ethanol under the guidance of digital subtraction angiography. Magnetic resonance imaging was used to evaluate the clinical outcomes of sclerotherapy. Complications were also evaluated.

RESULTS

The duration of follow-up was a mean of 8 months (range, 3 to 22). Of the 60 patients, 22 were treated once and 38 were treated 2 to 18 times (mean 2.6 times/patient). The mean total volume of ethanol in 60 patients was 11.2 mL (range, 0.5 to 230 mL). Of the 60 patients, 56 had complete volume reduction and a marked response after treatment. No severe skin necrosis or permanent nerve damage occurred.

CONCLUSION

Percutaneous sclerotherapy with absolute ethanol under the guidance of venography is a safe and effective treatment for venous malformations in the face and neck.

摘要

目的

本研究的目的是评估使用无水乙醇进行硬化治疗对面颈部静脉畸形的疗效。

患者与方法

我们对60例连续的面颈部静脉畸形患者在数字减影血管造影引导下用无水乙醇进行硬化治疗。采用磁共振成像评估硬化治疗的临床疗效。同时也对并发症进行了评估。

结果

随访时间平均为8个月(范围3至22个月)。60例患者中,22例接受了1次治疗,38例接受了2至18次治疗(平均每位患者2.6次)。60例患者无水乙醇的平均总量为11.2 mL(范围0.5至230 mL)。在60例患者中,56例治疗后体积完全缩小且反应明显。未发生严重皮肤坏死或永久性神经损伤。

结论

在静脉造影引导下经皮用无水乙醇进行硬化治疗是一种对面颈部静脉畸形安全有效的治疗方法。

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