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透析血管通路的研究现状。

Status of research in vascular access for dialysis.

机构信息

Denver Nephrology, Ste 240 Denver, CO, USA.

出版信息

Nephrol Dial Transplant. 2010 Nov;25(11):3682-6. doi: 10.1093/ndt/gfq267. Epub 2010 May 19.

DOI:10.1093/ndt/gfq267
PMID:20484302
Abstract

BACKGROUND

Vascular access issues impose a major financial burden to health care and can be associated with increased morbidity and mortality. In this context, strategies, guidelines and available published information become important tools for health-care facilities and workers. While published data form a sound basis of formulating clinical practice guidelines for vascular access (VA), quality of the medical information is critically important. This study investigates the current status of VA publications.

METHODS

A PubMed search was performed to capture all articles related to dialysis vascular access published from January 1997 to December 2009. The articles were categorized by publication type, study subject, year of publication and specialty of the authors.

RESULTS

A total of 2260 articles from 60 medical journals were identified. Insignificant publications (letters/communications, n = 125) were excluded from the analysis. Therefore, 2135 articles formed the basis for analysis. Sixteen of the 60 journals routinely published on vascular access and generated 1747 articles [nephrology = 7 (publications = 782); radiology = 4 (publications = 333); surgery = 5 (publications = 486)], while 44/60 journals published scarcely and produced 388 articles over the 13-year period. Overall, 1213 (57%) of the articles were published by the direct involvement of nephrologists [nephrologists alone (n = 564); nephrologists in collaboration with others (n = 649)]. There were 1194 observational studies, 444 case reports/series, 375 review/editorials, 51 basic research, 12 meta-analyses and 59 randomized controlled trials published over the 13-year period. The average impact factor for nephrology, radiology and surgery journals that routinely published on vascular access was 4.425, 3.099 and 2.679, respectively.

CONCLUSIONS

Despite an increased rate of scholarly activity in the area of vascular access, there remains a significant challenge ahead due to the lack of randomized controlled trials and research focusing on the biology of vascular access stenosis.

摘要

背景

血管通路问题给医疗保健带来了重大的经济负担,并且可能与发病率和死亡率的增加有关。在这种情况下,策略、指南和现有的已发表信息成为医疗保健机构和工作人员的重要工具。虽然已发表的数据为制定血管通路(VA)的临床实践指南提供了坚实的基础,但医疗信息的质量至关重要。本研究调查了 VA 出版物的现状。

方法

对 1997 年 1 月至 2009 年 12 月期间发表的所有与透析血管通路相关的文章进行了 PubMed 搜索。根据出版类型、研究对象、出版年份和作者专业对文章进行了分类。

结果

从 60 种医学期刊中总共确定了 2260 篇文章。将无意义的出版物(信件/通讯,n=125)排除在分析之外。因此,2135 篇文章构成了分析的基础。60 种期刊中有 16 种定期发表血管通路相关文章,共发表了 1747 篇文章[肾脏病学=7(出版物=782);放射学=4(出版物=333);外科学=5(出版物=486)],而 60 种期刊中的 44 种期刊出版量较少,在 13 年期间共发表了 388 篇文章。总体而言,1213 篇(57%)文章是由肾脏病专家直接参与发表的[肾脏病专家单独发表(n=564);肾脏病专家与其他人合作发表(n=649)]。在这 13 年期间,共发表了 1194 项观察性研究、444 例病例报告/系列、375 篇综述/社论、51 篇基础研究、12 篇荟萃分析和 59 篇随机对照试验。定期发表血管通路相关文章的肾脏病学、放射学和外科学期刊的平均影响因子分别为 4.425、3.099 和 2.679。

结论

尽管血管通路领域的学术活动率有所提高,但由于缺乏随机对照试验和专注于血管通路狭窄生物学的研究,仍然面临着重大挑战。

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