Department of Clinical and Experimental Medicine, University of Ferrara, Ferrara, Italy.
Dermatology. 2010 Aug;221(1):55-62. doi: 10.1159/000278259. Epub 2010 May 13.
Very few dermoscopic investigations into pigmented genital lesions have been performed to date. To the best of our knowledge, no dermoscopical description of vulvar melanocytic nevi (MN) has yet been proposed.
Our aims were to analyze the dermoscopic features of vulvar MN and to review the literature of dermoscopy of the vulvar area.
Among 74 women presenting 84 vulvar pigmented lesions, 10 who received a visual diagnosis of MN were submitted to dermoscopic and histopathological analysis.
Histology confirmed the clinical diagnosis of MN in 8 out of 10 cases, while the remaining 2 pigmented lesions were diagnosed as seborrheic keratosis. Vulvar MN were generally found to share similar dermoscopic patterns with their cutaneous equivalent.
Although further observation will be necessary to provide additional data and establish key morphological criteria and/or algorithms useful for differentiating between melanocytic and nonmelanocytic vulvar lesions, dermoscopy should be considered an investigative tool, as clinical observation alone may not be sufficient for accurate diagnosis.
迄今为止，针对生殖器色素性病变的皮肤镜检查研究甚少。据我们所知，目前尚未提出外阴黑素细胞痣（MN）的皮肤镜描述。
我们旨在分析外阴 MN 的皮肤镜特征，并复习外阴区域皮肤镜检查的文献。
在 74 名出现 84 处外阴色素性病变的女性中，10 名接受 MN 视觉诊断的患者接受了皮肤镜和组织病理学分析。
组织学在 8 例中证实了临床诊断为 MN，而其余 2 处色素性病变被诊断为脂溢性角化病。外阴 MN 通常与皮肤 MN 具有相似的皮肤镜模式。
尽管需要进一步观察以提供更多数据并建立有用的形态学标准和/或算法，用于区分黑素细胞和非黑素细胞性外阴病变，但皮肤镜检查应被视为一种研究工具，因为仅凭临床观察可能不足以进行准确诊断。
