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自噬相关分子和过程的综合词汇表。

A comprehensive glossary of autophagy-related molecules and processes.

机构信息

Life Sciences Institute and Department of Molecular, Cellular and Developmental Biology, University of Michigan, Ann Arbor, MI, USA.

出版信息

Autophagy. 2010 May;6(4):438-48. doi: 10.4161/auto.6.4.12244. Epub 2010 May 16.

Abstract

Autophagy is a rapidly expanding field in the sense that our knowledge about the molecular mechanism and its connections to a wide range of physiological processes has increased substantially in the past decade. Similarly, the vocabulary associated with autophagy has grown concomitantly. This fact makes it difficult for readers, even those who work in the field, to keep up with the ever-expanding terminology associated with the various autophagy-related processes. Accordingly, we have developed a comprehensive glossary of autophagy-related terms that is meant to provide a quick reference for researchers who need a brief reminder of the regulatory effects of transcription factors or chemical agents that induce or inhibit autophagy, the function of the autophagy-related proteins, or the role of accessory machinery or structures that are associated with autophagy.

摘要

自噬是一个迅速发展的领域,在过去的十年中,我们对其分子机制及其与广泛的生理过程的联系的了解有了实质性的增加。同样,与自噬相关的词汇也相应地增加了。这一事实使得即使是那些在该领域工作的读者也很难跟上与各种自噬相关过程相关的术语的不断扩展。因此,我们开发了一个全面的自噬相关术语词汇表,旨在为那些需要快速了解转录因子或诱导或抑制自噬的化学试剂的调节作用、自噬相关蛋白的功能、或与自噬相关的辅助机械或结构的作用的研究人员提供一个快速参考。

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