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应用颈侧皮瓣修复口腔颌面部缺损的临床与实验研究

Reconstruction by lateral cervical flap of perioral and oral cavity: clinical and experimental studies.

作者信息

Kummoona Raja

机构信息

Council of Maxillofacial Surgery, Iraqi Board for Medical Specialization, Medical City, Baghdad, Iraq.

出版信息

J Craniofac Surg. 2010 May;21(3):660-5. doi: 10.1097/SCS.0b013e3181d7a760.

Abstract

These clinical studies include 75 patients, followed up for 2 to 5 years: 37 females and 38 males. Age ranged between 5 and 81 years (median, 46 years). These cases were seen during a period of 6 years. There were 61 cases of oral squamous cell carcinoma; these cases include 25 cases of well-differentiated squamous cell carcinoma, 24 cases of moderately differentiated squamous cell carcinoma, and 12 cases of poorly differentiated squamous cell carcinoma. These cases were treated by adjuvant chemotherapy with radical surgery and deep x-ray therapy. In 23 cases, the lateral cervical flap (LCF) was used as an excess for radical resection of supraomohyoid neck dissection; in 10 cases, the LCF was used for reconstruction of cases with posttraumatic missile injuries, and in 4 cases, platysma muscle flap was used for reconstruction of underdeveloped masseter muscle in cases with mild hemifacial microsomia. Experimental studies were performed on rabbits for reconstruction of the lateral side of the tongue and submental region to assess the viability of LCF. In conclusion, the flap proved to be an ideal and most reliable flap for reconstruction of both perioral and oral defects after radical cancer surgery and posttraumatic missile injury deformities.

摘要

这些临床研究包括75例患者,随访2至5年:女性37例,男性38例。年龄在5岁至81岁之间(中位数为46岁)。这些病例是在6年期间观察到的。有61例口腔鳞状细胞癌;这些病例包括25例高分化鳞状细胞癌、24例中分化鳞状细胞癌和12例低分化鳞状细胞癌。这些病例采用辅助化疗联合根治性手术和深部X线治疗。23例中,颈外侧皮瓣(LCF)用于舌骨上颈部清扫根治性切除的补充;10例中,LCF用于创伤后导弹伤病例的重建,4例中,颈阔肌肌瓣用于轻度半侧颜面短小畸形病例咬肌发育不良的重建。对家兔进行了重建舌外侧和颏下区域的实验研究,以评估LCF的生存能力。总之,该皮瓣被证明是根治性癌症手术后及创伤后导弹伤畸形后重建口周和口腔缺损的理想且最可靠的皮瓣。

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