青少年肝脾 γδ T 细胞淋巴瘤患者以视网膜出血为首发表现
Retinal hemorrhages as a presenting sign in an adolescent patient with hepatosplenic gamma-delta T-cell lymphoma.
机构信息
Department of Pediatrics, Walter Reed Army Medical Center, Washington, District of Columbia 20307, USA.
出版信息
Pediatr Blood Cancer. 2010 Jul 15;55(1):190-2. doi: 10.1002/pbc.22485.
Hepatosplenic gamma-delta T-cell lymphoma is a very rare, aggressive form of peripheral lymphoma first recognized in 1990. Patients often present with organomegaly, anemia, adenopathy, and B symptoms. Rarely in the literature is a pediatric patient described with this subtype of peripheral T-cell lymphoma. Also, retinal hemorrhages have never been described as a presenting symptom of hepatosplenic gamma-delta T-cell lymphoma. We describe an adolescent patient with hepatosplenic gamma-delta T-cell lymphoma who presented with retinal hemorrhages, massive splenomegaly, bone marrow involvement, and B symptoms.
肝脾γδ T 细胞淋巴瘤是一种非常罕见且侵袭性的外周淋巴瘤，于 1990 年首次被认识。患者常表现为肝脾肿大、贫血、淋巴结病和 B 症状。文献中罕见描述此类儿科患者外周 T 细胞淋巴瘤。此外，视网膜出血从未被描述为肝脾γδ T 细胞淋巴瘤的首发症状。我们描述了一例青少年肝脾γδ T 细胞淋巴瘤患者，其表现为视网膜出血、巨脾、骨髓受累和 B 症状。
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