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New initiative speeds tuberculosis drug development: novel drug regimens become possible in years, not decades.

作者信息

Spigelman Mel, Woosley Raymond, Gheuens Jan

出版信息

Int J Tuberc Lung Dis. 2010 Jun;14(6):663-4.

PMID:20487601
Abstract
摘要

相似文献

1
New initiative speeds tuberculosis drug development: novel drug regimens become possible in years, not decades.新举措加速结核病药物研发:数年内即可实现新型药物疗法,而非数十年。
Int J Tuberc Lung Dis. 2010 Jun;14(6):663-4.
2
[Development of antituberculous drugs: current status and future prospects].[抗结核药物的研发:现状与未来前景]
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Challenges in tuberculosis drug research and development.结核病药物研发中的挑战。
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[Tuberculosis--social, economic and political problem. Two billions of people are infected].[结核病——社会、经济和政治问题。二十亿人受到感染]
Lakartidningen. 2004 Jan 29;101(5):390-4.
5
The global alliance for tuberculosis drug development--accomplishments and future directions.全球结核病药物开发联盟——成就与未来方向。
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New initiative to increase access to tuberculosis (TB) drugs.增加结核病药物可及性的新举措。
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[Limited epidemic of tuberculosis among young socially dysadapted individuals].
Probl Tuberk Bolezn Legk. 2006(3):40-1.
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Emerging drugs for active tuberculosis.用于活动性结核病的新型药物。
Semin Respir Crit Care Med. 2008 Oct;29(5):552-9. doi: 10.1055/s-0028-1085706. Epub 2008 Sep 22.
9
Is the development of a new tuberculosis vaccine possible?开发一种新的结核病疫苗是否可行?
Nat Med. 2000 Sep;6(9):955-60. doi: 10.1038/79631.
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Guidance for national tuberculosis programmes on the management of tuberculosis in children. Chapter 2: anti-tuberculosis treatment in children.国家结核病规划儿童结核病管理指南。第2章:儿童抗结核治疗
Int J Tuberc Lung Dis. 2006 Nov;10(11):1205-11.

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Pharmacodynamics and Bactericidal Activity of Bedaquiline in Pulmonary Tuberculosis.贝达喹啉治疗肺结核的药效学和杀菌活性。
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Spectinamides are effective partner agents for the treatment of tuberculosis in multiple mouse infection models.在多种小鼠感染模型中, Spectinamides是治疗结核病的有效联合用药。
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Computational pharmacokinetics/pharmacodynamics of rifampin in a mouse tuberculosis infection model.
利福平在小鼠结核感染模型中的计算药代动力学/药效学
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Aptamer-based proteomic signature of intensive phase treatment response in pulmonary tuberculosis.基于适配体的结核分枝杆菌强化治疗期反应的蛋白质组学特征。
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Bedaquiline - The first ATP synthase inhibitor against multi drug resistant tuberculosis.贝达喹啉——首个针对耐多药结核病的ATP合酶抑制剂。
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Tuberculosis: From an incurable scourge to a curable disease - journey over a millennium.结核病:从无药可救的瘟疫到可治愈的疾病——千年历程。
Indian J Med Res. 2013 Mar;137(3):455-93.
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A physiologically based pharmacokinetic model of rifampin in mice.在小鼠体内利福平的生理基于药代动力学模型。
Antimicrob Agents Chemother. 2013 Apr;57(4):1763-71. doi: 10.1128/AAC.01567-12. Epub 2013 Jan 28.
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Sterilizing activities of novel combinations lacking first- and second-line drugs in a murine model of tuberculosis.新型组合药物在结核病小鼠模型中缺乏一线和二线药物的杀菌活性。
Antimicrob Agents Chemother. 2012 Jun;56(6):3114-20. doi: 10.1128/AAC.00384-12. Epub 2012 Apr 2.
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Drug-resistant tuberculosis: emerging treatment options.耐药结核病:新出现的治疗选择
Clin Pharmacol. 2011;3:51-67. doi: 10.2147/CPAA.S11597. Epub 2011 Dec 14.