Hyman R A, Loring M F, Liebeskind A L, Naidich J B, Stein H L
Neuroradiology. 1978 Feb 17;14(5):213-8. doi: 10.1007/BF00418618.
A prospective study was initiated to evaluate computed tomography as a method for monitoring therapeutically induced changes in brain tumors. Early postoperative scans may be misleading in the evaluation of residual tumor because of trauma to the blood-brain barrier during operation. The size of the dominant mass (17/25), enhancement (11/25), edema (11/25), and ventricular distortion (14/25) were decreased in many patients after radiation therapy. Occasional tumors increased in size during radiation therapy (3/25). Enlargement of the lateral ventricles developed in 9 of 25 patients. Computed tomography offers definite advantages over nuclide brain scans, angiography and other diagnostic studies for evaluating therapeutically induced changes in brain tumors.
开展了一项前瞻性研究，以评估计算机断层扫描作为监测脑肿瘤治疗引起变化的一种方法。术后早期扫描在评估残留肿瘤时可能会产生误导，因为手术期间血脑屏障受到了创伤。许多患者在放疗后，主要肿块大小（17/25）、强化程度（11/25）、水肿情况（11/25）及脑室变形（14/25）均有所减轻。偶尔有肿瘤在放疗期间增大（3/25）。25名患者中有9名出现侧脑室扩大。在评估脑肿瘤治疗引起的变化方面，计算机断层扫描比核素脑扫描、血管造影及其他诊断研究具有明显优势。
