Department of Cardiology, The John Ochsner Heart and Vascular Institute, New Orleans, Louisiana 70121, USA.
JACC Cardiovasc Interv. 2010 May;3(5):467-74. doi: 10.1016/j.jcin.2010.04.002.
In the past 3 years, there have been significant developments in the field of carotid revascularization, including: 1) the results of a large primary stroke prevention trial; 2) the emergence of novel platforms for emboli protection; 3) improved characterization of the high-risk carotid artery stent (CAS) patient; 4) completion of several very large post-market surveillance (PMS) trials of CAS in high-surgical-risk patients; and 5) the completion of 4 large randomized controlled trials comparing CAS with carotid endarterectomy in average-risk patients. The purpose of this review is to update the current status of revascularization therapies to reduce stroke in patients with extracranial carotid artery disease with a focus on the most recent developments regarding the role of CAS.
在过去的 3 年中，颈动脉血运重建领域取得了重大进展，包括：1）一项大型首发卒中预防试验的结果；2）新型栓子保护平台的出现；3）高危颈动脉支架置入（CAS）患者特征的改善；4）多项高危颈动脉支架置入患者大型上市后监测（PMS）试验完成；5）4 项比较平均风险患者中颈动脉内膜切除术与颈动脉支架置入术的大型随机对照试验完成。本文旨在更新目前的血运重建治疗策略，以降低颅外颈动脉疾病患者的卒中风险，重点关注最新的关于颈动脉支架置入术作用的研究进展。
