Kim Gyu-Tae, Lee Jung-Kyo, Choi Byung-Joon, Kim Jin, Han Sun-Hee, Kwon Yong-Dae
Departments of Oral & Maxillofacial Radiology, Kyung Hee University Medical Center, College of Dentistry, Yonsei University, Seoul, Republic of Korea.
J Craniofac Surg. 2010 Mar;21(2):601-3. doi: 10.1097/SCS.0b013e3181d08ca8.
Malignant transformation of fibrous dysplasia (FD), which was first introduced by Coley and Steward is very rare. We present a case of malignant transformation of monostotic mandibular FD after 2 surgical excisions, 20 and 15 years ago, respectively. The treatment choice of FD is usually conservative. With the advanced surgical techniques, radical excisions followed by immediate reconstruction have been reported. However, the decision criteria are still controversial and we might think that radical treatment is a good method for recurrent lesions based on the recent literatures. The case discussed here is of sarcomatous transformation of a recurrent FD.
纤维发育不良（FD）的恶性转化最早由科利和斯图尔特提出，极为罕见。我们报告一例单发性下颌骨FD的恶性转化病例，该患者分别于20年前和15年前接受了两次手术切除。FD的治疗选择通常较为保守。随着外科技术的进步，有报道称可进行根治性切除并立即重建。然而，决策标准仍存在争议，基于近期文献，我们可能认为根治性治疗是复发病变的一种好方法。此处讨论的病例是复发性FD的肉瘤样转化。
