Richter G H, Flachowsky G
Sektion Tierproduktion und Veterinärmedizin, Karl-Marx-Universität Leipzig.
Arch Tierernahr. 1991 Jan;41(1):85-96. doi: 10.1080/17450399109424735.
The influence of salinomycin (0, 15, 30 and 60 mg per animal and day) on apparent digestibility of artificially dried grass was investigated in four experiments with five wether each. Three long term individual feeding experiments (210 to 252 days) with 72 growing bulls were carried out. The influence of various salinomycin levels (100 to 300 mg per animal and day) were investigated on parameters of rumen fermentation as well as fattening and slaughtering results. Salinomycin decreased insignificantly (P greater than 0.05) the apparent digestibility of organic matter (71.0; 70.1; 68.7 and 68.4%) and crude carbohydrates (71.8; 70.3; 69.2 and 68.5% resp.). The digestibility of other nutrients was not influenced. Supplementation of salinomycin reduced molar concentration of acetate (49 to 115) and butyrate (22 to 82) and increased propionate (110 to 199 mmoles per mol) in rumen liquid. Dry matter intake of bulls declined (0.8%, 13.5 and 24.6; 4.7% of experiments 1 to 3) when salinomycin was added. Daily weight gain (6.5 and 1.0%) and feed efficiency (6.8 and 6.3%) of bulls supplemented with salinomycin were improved in experiments 1 and 3. Significant decrease of feed intake of bulls of experiment 2 affected decline of weight gain probably as consequence of high salinomycin levels. Slaughtering results (except experiment 2) and body composition of bulls were not significantly influenced by salinomycin. Under consideration of own results and some references 10 to 20 mg per kg dry matter or 50 to 150 mg salinomycin per fattening bull and day are recommended as optimal level.
在四项实验中，每项实验用五只阉羊，研究了沙利霉素（每只动物每天0、15、30和60毫克）对人工干燥草表观消化率的影响。对72头生长公牛进行了三项长期个体饲养实验（210至252天）。研究了不同沙利霉素水平（每只动物每天100至300毫克）对瘤胃发酵参数以及育肥和屠宰结果的影响。沙利霉素使有机物（分别为71.0%、70.1%、68.7%和68.4%）和粗碳水化合物（分别为71.8%、70.3%、69.2%和68.5%）的表观消化率略有下降（P大于0.05）。其他营养物质的消化率未受影响。添加沙利霉素可降低瘤胃液中乙酸（49至115）和丁酸（22至82）的摩尔浓度，并增加丙酸（每摩尔110至199毫摩尔）。添加沙利霉素时，公牛的干物质摄入量下降（实验1至3分别下降0.8%、13.5%和24.6%；4.7%）。在实验1和3中，添加沙利霉素的公牛的日增重（分别提高6.5%和1.0%）和饲料效率（分别提高6.8%和6.3%）有所改善。实验2中公牛采食量的显著下降可能是由于沙利霉素水平过高导致体重增加下降。沙利霉素对屠宰结果（实验2除外）和公牛的身体组成没有显著影响。综合自身结果和一些参考文献，建议每千克干物质添加10至20毫克或每头育肥牛每天添加50至150毫克沙利霉素作为最佳水平。
