波兰入选全球近期诊断心房颤动患者注册研究（RecordAF）的患者的基线特征。

Baseline characteristics of patients from Poland enrolled in the global registry of patients with recently diagnosed atrial fibrillation (RecordAF).

机构信息

1st Department of Cardiology, Warsaw Medical University, Warsaw, Poland.

出版信息

Kardiol Pol. 2010 May;68(5):546-54.

PMID:20491018

Abstract

BACKGROUND

The RecordAF study is the first worldwide, prospective, observational survey on the management of patients with recently diagnosed atrial fibrillation (AF).

AIM

This paper presents the baseline characteristics of the Polish patients enrolled in this registry.

METHODS

The registry enrolled patients > or = 18 years old with recently diagnosed AF (< or = 12 months from diagnosis), eligible for rhythm or rate control strategy. The planned follow-up is 12 months. The aim of the registry is to prospectively assess the efficacy of treatment defined as (a) maintenance of sinus rhythm or (b) optimal rate control, as well as (c) the incidence of cardiovascular events.

RESULTS

A total of 303 Polish patients were enrolled in 21 centres across Poland (mean age 63 +/- 12 years, M/F ratio 174/129). Hypertension was present in 71.5% of the study subjects, ischaemic heart disease in 18.9%, and diabetes in 12.3%. In 47 (15.6%) patients, no potential cause of AF could be established. Symptoms related to AF were reported by 89.1% of patients. Mean duration of AF history was 2.9 +/- 3.5 months. At the time of inclusion, 191 (63.0%) patients were in sinus rhythm, and 211 (69.6%) patients were assigned to rhythm control strategy. Rhythm control strategy was chosen more frequently in patients with a history of paroxysmal AF and those in sinus rhythm at inclusion. Rate control strategy was chosen more frequently in those with a history of persistent AF in the previous year or presenting with AF at inclusion.

CONCLUSIONS

Analysis of the baseline characteristics of the Polish population of the RecordAF study indicates a high prevalence of co-morbidities among patients with AF. The choice of treatment strategy was associated with rhythm status at inclusion and AF pattern within the previous 12 months. The RecordAF study will provide prospective data on treatment decisions and treatment success of rhythm- or rate-control strategies in patients with AF treated by office- or hospital-based cardiologists.

摘要

背景

RecordAF 研究是全球首个针对近期诊断为心房颤动（AF）患者管理的前瞻性观察性调查。

目的

本文介绍了该注册研究中纳入的波兰患者的基线特征。

方法

该注册研究纳入了年龄≥18 岁、近期诊断为 AF（从诊断起<或=12 个月）、适合节律或心率控制策略的患者。计划随访时间为 12 个月。该注册研究的目的是前瞻性评估治疗效果，定义为（a）维持窦性心律或（b）最佳心率控制，以及（c）心血管事件的发生率。

结果

共 303 名波兰患者在波兰 21 个中心入组（平均年龄 63±12 岁，男/女比例 174/129）。71.5%的研究对象患有高血压，18.9%患有缺血性心脏病，12.3%患有糖尿病。在 47 名（15.6%）患者中，无法确定 AF 的潜在原因。89.1%的患者报告有与 AF 相关的症状。AF 病史的平均持续时间为 2.9±3.5 个月。入组时，191 名（63.0%）患者处于窦性心律，211 名（69.6%）患者被分配至节律控制策略。有阵发性 AF 病史和入组时处于窦性心律的患者更倾向于选择节律控制策略。在过去 1 年内有持续性 AF 病史或入组时出现 AF 的患者更倾向于选择心率控制策略。