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Impact of γ-Amino Acid Residue Preorganization on α/γ-Peptide Foldamer Helicity in Aqueous Solution.
J Am Chem Soc. 2016 Aug 31;138(34):10766-9. doi: 10.1021/jacs.6b06177. Epub 2016 Aug 16.
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Crystallographic characterization of helical secondary structures in alpha/beta-peptides with 1:1 residue alternation.
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Helical folding in heterogeneous foldamers without inter-residual backbone hydrogen-bonding.
Chem Commun (Camb). 2012 Sep 14;48(71):8922-4. doi: 10.1039/c2cc33235c. Epub 2012 Jul 31.
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Folding and Assembly of Short α, β, γ-Hybrid Peptides: Minor Variations in Sequence and Drastic Differences in Higher-Level Structures.
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Structural Investigation of Hybrid Peptide Foldamers Composed of α-Dipeptide Equivalent β-Oxy-δ -amino Acids.
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Tackling Undruggable Targets with Designer Peptidomimetics and Synthetic Biologics.
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Unnatural helical peptidic foldamers as protein segment mimics.
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Environmental Modulation of Chiral Prolinamide Catalysts for Stereodivergent Conjugate Addition.
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α,ε-Hybrid Peptide Foldamers: Self-Assembly of Peptide with Trans Carbon-Carbon Double Bonds in the Backbone and Its Saturated Analogue.
ACS Omega. 2018 Aug 8;3(8):8760-8768. doi: 10.1021/acsomega.8b00832. eCollection 2018 Aug 31.
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Impact of γ-Amino Acid Residue Preorganization on α/γ-Peptide Foldamer Helicity in Aqueous Solution.
J Am Chem Soc. 2016 Aug 31;138(34):10766-9. doi: 10.1021/jacs.6b06177. Epub 2016 Aug 16.
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Heterogeneous H-bonding in a foldamer helix.
J Am Chem Soc. 2015 May 27;137(20):6484-7. doi: 10.1021/jacs.5b03382. Epub 2015 May 14.
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Evaluation of a cyclopentane-based γ-amino acid for the ability to promote α/γ-peptide secondary structure.
J Org Chem. 2013 Dec 20;78(24):12351-61. doi: 10.1021/jo401501g. Epub 2013 Dec 5.
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Differential impact of β and γ residue preorganization on α/β/γ-peptide helix stability in water.
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New preorganized γ-amino acids as foldamer building blocks.
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本文引用的文献

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A beta/gamma motif to mimic alpha-helical turns in proteins.
Chembiochem. 2010 Feb 15;11(3):335-9. doi: 10.1002/cbic.200900700.
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Evaluation of triazolamers as active site inhibitors of HIV-1 protease.
Bioorg Med Chem Lett. 2009 Nov 1;19(21):6023-6. doi: 10.1016/j.bmcl.2009.09.049. Epub 2009 Sep 17.
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Structural and biological mimicry of protein surface recognition by alpha/beta-peptide foldamers.
Proc Natl Acad Sci U S A. 2009 Sep 1;106(35):14751-6. doi: 10.1073/pnas.0902663106. Epub 2009 Aug 17.
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Identification of a beta3-peptide HIV fusion inhibitor with improved potency in live cells.
Bioorg Med Chem Lett. 2009 Jul 15;19(14):3736-8. doi: 10.1016/j.bmcl.2009.05.032. Epub 2009 May 15.
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De novo design and in vivo activity of conformationally restrained antimicrobial arylamide foldamers.
Proc Natl Acad Sci U S A. 2009 Apr 28;106(17):6968-73. doi: 10.1073/pnas.0811818106. Epub 2009 Apr 9.

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