Department of Bio-Physical Medical and Dental Sciences and Technologies, University of Genova, Italy.
Clin Implant Dent Relat Res. 2012 Jun;14(3):373-9. doi: 10.1111/j.1708-8208.2010.00274.x. Epub 2010 May 11.
Insufficient alveolar bone height often prevents the placement of standard dental implants in the posterior part of edentulous maxilla. In order to increase adequately the vertical dimension of the reabsorbed alveolar process, a sinus lift procedure is often necessary. The aim of this study was to evaluate histologic results of a prehydrated corticocancellous porcine bone used in maxillary sinus augmentation.
Patients (age 18-70 years) with a residual bone height requiring a maxillary sinus augmentation procedure to place dental implants were eligible for this study. All patients were treated with the same surgical technique consisting of sinus floor augmentation via a lateral approach. The space obtained by elevation of the mucosa wall was grafted with prehydrated and collagenated corticocancellous porcine bone. Biopsies were harvested 6 months after the augmentation procedures.
Twenty-four patients were enrolled. The mean percentage of new formed bone was 43.9 ± 18.6% (range 7.5-100%), whereas the mean percentage of residual graft material was 14.2 ± 13.6% (range 0-41.9%). The new bone/residual graft material ratio in the maxillary sinuses was 3.1. The mean soft tissues percentage was 41.8 ± 22.7% (range 0-92.5%).
The present study suggested that porcine bone showed excellent osteoconductive properties and could be used successfully for sinus augmentation. Moreover, the porcine bone showed a high percentage of reabsorption after 6 months; this might be because of the presence of collagen and the porosity of the graft material.
牙槽骨高度不足常导致无牙上颌后牙区无法植入标准种植体。为了充分增加吸收牙槽嵴的垂直高度,常需要进行窦底提升术。本研究旨在评估用于上颌窦提升的预水合皮质松质猪骨的组织学结果。
本研究纳入了需要上颌窦提升术以植入种植体的患者(年龄 18-70 岁)。所有患者均采用相同的手术技术进行治疗,即经外侧入路行窦底提升术。通过提升黏膜壁获得的空间用预水合和胶原化的皮质松质猪骨进行移植。在提升术后 6 个月采集活检样本。
本研究共纳入 24 例患者。新形成骨的平均百分比为 43.9 ± 18.6%(范围 7.5-100%),而残留移植物材料的平均百分比为 14.2 ± 13.6%(范围 0-41.9%)。上颌窦内新骨/残留移植物材料的比值为 3.1。软组织的平均百分比为 41.8 ± 22.7%(范围 0-92.5%)。
本研究表明猪骨具有良好的成骨特性,可成功用于窦底提升。此外,猪骨在 6 个月后有较高的吸收率,这可能是由于胶原的存在和移植物材料的多孔性。