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在上颌窦黏膜提升与种植体植入同时进行且不使用植骨材料的情况下,上颌窦底的骨形成:对20例接受44枚Astra Tech种植体治疗患者的评估

Bone formation at the maxillary sinus floor following simultaneous elevation of the mucosal lining and implant installation without graft material: an evaluation of 20 patients treated with 44 Astra Tech implants.

作者信息

Thor Andreas, Sennerby Lars, Hirsch Jan Michael, Rasmusson Lars

机构信息

Department of Surgical Sciences, Oral and Maxillofacial Surgery, Uppsala University Hospital, Uppsala, Sweden.

出版信息

J Oral Maxillofac Surg. 2007 Jul;65(7 Suppl 1):64-72. doi: 10.1016/j.joms.2006.10.047.

Abstract

PURPOSE

Restoration of lost dentition in the severely artrophic posterior maxilla has for the last 2 decades been successfully treated with various sinus augmentation techniques and installation of dental implants. The use of graft material is anticipated to be necessary; however, recent studies have demonstrated that the mere lifting of the sinus mucosal lining and simultaneous placement of implants result in bone formation. This study was conducted in order to evaluate simultaneous sinus mucosal lining elevation and installation of dental implants without any graft material.

PATIENTS AND METHODS

Twenty patients were consecutively included from November 2001 to June 2004. Forty-four Astra ST dental implants (Astra Tech AB, Mölndal, Sweden) with a diameter of 4.5 mm or 5 mm were installed in 27 sinuses. A sinus lift was performed where a cortical window was removed from the maxillary anterior sinus wall. The sinus mucosal lining was elevated and implants installed in the residual subantral bone. The cortical window was thereafter replaced and the incision closed. The remaining bone height was recorded during surgery as well as perforations of the sinus mucosal lining. After 6 months of healing, abutments were connected (the series included 5 1-stage procedures). Clinical and radiological follow-up after loading was performed up to 4 years after implant installation.

RESULTS

Patients tolerated the procedure well as few complications were observed. Firm primary stability was achieved for all implants at installation with bone levels in residual bone of 2 to 9 mm. Perforations of the maxillary sinus mucosal lining occurred in 11 of the 27 operated sinuses (41%). One implant was lost during a mean follow-up of 27.5 months (range, 14 to 45 months) giving an implant survival rate of 97.7%. The average gain of bone at the sinus floor was 6.51 mm (SD = 2.49, 44 implants) including all measured implants after a minimum of 1 year follow-up. Marked bone formation was observed around long implants and also when the residual bone below the sinus was diminutive.

CONCLUSIONS

The present study including 20 patients showed consistent bone formation at the maxillary sinus floor following simultaneous mucosal lining elevation and installation of implants. It is suggested that the use of this technique can reduce the risk for morbidity related to harvesting of bone grafts and eliminate costs for grafting materials.

摘要

目的

在过去20年中,严重萎缩的上颌后牙区牙列缺失已通过各种窦底提升技术和牙种植体植入得到成功治疗。预计需要使用移植材料;然而,最近的研究表明,单纯提升窦黏膜并同时植入种植体可导致骨形成。本研究旨在评估在不使用任何移植材料的情况下同时进行窦黏膜提升和牙种植体植入的效果。

患者与方法

2001年11月至2004年6月连续纳入20例患者。在27个窦中植入44颗直径为4.5毫米或5毫米的Astra ST牙种植体(瑞典莫恩达尔市Astra Tech AB公司)。在对上颌前窦壁去除皮质骨窗后进行窦底提升。提升窦黏膜并将种植体植入剩余的窦下骨。然后更换皮质骨窗并关闭切口。手术过程中记录剩余骨高度以及窦黏膜穿孔情况。愈合6个月后连接基台(该系列包括5例一期手术)。种植体植入后长达4年进行加载后的临床和放射学随访。

结果

患者对该手术耐受性良好,观察到的并发症较少。所有种植体植入时均获得了牢固的初期稳定性,剩余骨中的骨水平为2至9毫米。27个手术窦中有11个(41%)发生上颌窦黏膜穿孔。在平均27.5个月(范围14至45个月)的随访期间,有1颗种植体丢失,种植体存留率为97.7%。至少随访1年后,包括所有测量的种植体在内,窦底的平均骨增量为6.51毫米(标准差 = 2.49,44颗种植体)。在长种植体周围以及窦下方剩余骨量较少时均观察到明显的骨形成。

结论

本项纳入20例患者的研究表明,同时进行黏膜提升和种植体植入后,上颌窦底出现了一致的骨形成。建议使用该技术可降低与采集骨移植相关的发病风险并消除移植材料的成本。

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