Department of Surgery, Division of General Thoracic and Foregut Surgery, University of Minnesota, Minneapolis, Minnesota 55455, USA.
Ann Thorac Surg. 2010 Jun;89(6):S2168-73. doi: 10.1016/j.athoracsur.2010.03.022.
A giant hiatal hernia (HH) is a hernia that includes at least 30% of the stomach in the chest, although a uniform definition does not exist; most commonly, a giant HH is a type III hernia with a sliding and paraesophageal component. The etiology of giant HH is not entirely clear, and two potential mechanisms exist: (1) gastroesophageal reflux disease (GERD) leads to esophageal scarring and shortening with resulting traction on the gastroesophageal junction and gastric herniation; and (2) chronic positive pressure on the diaphragmatic hiatus combined with a propensity to herniation leads to gastric displacement into the chest, resulting in GERD. The short esophagus and GERD are key concepts to understanding the pathophysiology of giant HH, and these concepts are critical to address this problem appropriately. A successful repair of giant HH requires adherence to basic hernia repair principles (ie, hernia sac excision, tension-free repair), recognition and correction of a short esophagus, and a well-performed antireflux procedure. Recurrence rates for open giant HH repairs in expert hands range between 2% and 12%; large series have demonstrated that meticulous laparoscopic surgical technique can emulate the results of open giant HH repair.
巨大食管裂孔疝(HH)是一种疝,其中至少 30%的胃疝入胸腔,尽管尚未存在统一的定义;最常见的是,巨大 HH 是一种滑动型和食管旁型 III 型疝。巨大 HH 的病因尚不完全清楚,存在两种潜在机制:(1)胃食管反流病(GERD)导致食管瘢痕形成和缩短,继而对胃食管连接部和胃疝产生牵引;(2)膈裂孔处慢性正压与疝易发性相结合导致胃移位至胸腔,从而引发 GERD。短食管和 GERD 是理解巨大 HH 病理生理学的关键概念,这些概念对于正确解决这个问题至关重要。巨大 HH 的成功修复需要遵循基本疝修复原则(即疝囊切除、无张力修复)、识别和纠正短食管,并进行良好的抗反流手术。在专家手中,开放式巨大 HH 修复的复发率在 2%至 12%之间;大型系列研究表明,细致的腹腔镜手术技术可以模拟开放式巨大 HH 修复的结果。