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肺切除术后 30 天与 90 天的手术死亡率。

The 30- versus 90-day operative mortality after pulmonary resection.

机构信息

Section of Thoracic Surgery, Division of Cardiothoracic Surgery, Department of Surgery, University of Alabama at Birmingham, Birmingham, Albama 35294, USA.

出版信息

Ann Thorac Surg. 2010 Jun;89(6):1717-22; discussion 1722-3. doi: 10.1016/j.athoracsur.2010.01.069.

Abstract

BACKGROUND

The 30-day operative mortality rate after thoracotomy is well documented; however, the 90-day mortality rate is not and is not part of The Society of Thoracic Surgeons database.

METHODS

We performed a retrospective cohort study using a prospective database of patients who underwent elective thoracotomy and pulmonary resection. Mortality rates were compared with The Society of Thoracic Surgeons database. Multivariate analysis was used to identify predictors of mortality after discharge but within 30 and 90 days.

RESULTS

There were 1,845 operative patients between January 2002 and December 2008. Mortality was defined several ways. The overall discharge mortality was 3.1%; however, 18 patients (1.0%) died after discharge within 30 days and 44 patients (2.5%) died between 31 and 90 days. Sudden death (usually because of a cardiac event) was the most common cause of death in patients after discharge before postoperative day 30 and the second most common cause in those who died after discharge between days 31 and 90. These patients were more likely to have advanced age (p = 0.004), history of hypertension (p = 0.013), and coronary artery disease (p < 0.001).

CONCLUSIONS

A significant number of patients die after discharge within 90 days after pulmonary resection. The most common causes of death at home are "sudden death" and are more common in patients with a history of coronary artery disease. These patients may benefit from more diligent postoperative care. A prospective database with calls to patients and families is required to accurately obtain this information and to establish true outcomes. The Society of Thoracic Surgeons database as well as nonsurgical databases that show efficacies of medical therapy for specific ailments should consider adding 90-day mortality results.

摘要

背景

开胸手术后 30 天的手术死亡率有详细记录;然而,90 天的死亡率却没有记录,也不是胸外科医师学会数据库的一部分。

方法

我们对 2002 年 1 月至 2008 年 12 月期间接受择期开胸手术和肺切除术的患者进行了回顾性队列研究。死亡率与胸外科医师学会数据库进行了比较。采用多变量分析来确定出院后 30 天内和 90 天内死亡的预测因素。

结果

2002 年 1 月至 2008 年 12 月期间共有 1845 例手术患者。死亡率有几种定义方法。总的出院死亡率为 3.1%;然而,有 18 例(1.0%)患者在出院后 30 天内死亡,44 例(2.5%)患者在出院后 31 至 90 天内死亡。在术后第 30 天之前出院的患者中,猝死(通常是由于心脏事件)是死亡的最常见原因,在出院后第 31 至 90 天内死亡的患者中,猝死是第二常见原因。这些患者更可能年龄较大(p = 0.004)、有高血压病史(p = 0.013)和冠心病(p < 0.001)。

结论

手术后 90 天内有相当数量的患者出院后死亡。在家中死亡的最常见原因是“猝死”,在有冠心病病史的患者中更为常见。这些患者可能受益于更严格的术后护理。需要一个有患者和家属电话随访的前瞻性数据库,以准确获取这些信息并确定真实的结果。胸外科医师学会数据库以及显示特定疾病药物治疗疗效的非手术数据库应考虑添加 90 天死亡率结果。

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