Asano Y, Naritomi Y, Kimura H, Maeda Y, Kusaba T, Yoshizawa S, Shiraishi G
Munakata Medical Association Hospital, Fukuoka, Japan.
Ann Hematol. 1991 May;62(5):194-5. doi: 10.1007/BF01703149.
We attempted treatment with low-dose aclarubicin (ACR), a new anthracycline, in a 66-year-old man with blastic transformation of essential thrombocythemia (ET). Two courses of ACR (20 mg/day x 7 days) were given intravenously. He showed a good response to this therapy without severe side effects. He has since maintained a state of prolonged remission. These observations indicate that low-dose ACR may be beneficial for management of the blastic transformation of ET.
