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双眼木糖氧化无色杆菌角膜炎继发于准分子激光原位角膜磨镶术。

Bilateral Achromobacter xylosoxidans keratitis after laser in situ keratomileusis.

机构信息

Department of Ophthalmology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.

出版信息

J Cataract Refract Surg. 2010 Jun;36(6):1045-7. doi: 10.1016/j.jcrs.2010.03.024.

Abstract

A 31-year-old man was referred to us 2 months after bilateral laser in situ keratomileusis (LASIK). On presentation, the corrected distance visual acuity was hand motion in the right eye and 20/25 in the left eye. Slitlamp examination showed a diffuse central stromal infiltrate, flap melting, and hypopyon in the right eye and marked interface opacities with crystal-like edges in the left eye. Flap lift and irrigation were performed. Because of the progressive keratitis, penetrating keratoplasty (PKP) was done in both eyes. Achromobacter xylosoxidans was isolated from both corneal buttons, and therapy was changed to chloramphenicol prednisolone eyedrops 8 times a day and intravenous meropenem 500 mg 3 times a day according to sensitivity testing. Two months after surgery, both transplants remained clear.

摘要

一名 31 岁男性在双眼 LASIK 激光原位角膜磨镶术后 2 个月来我院就诊。就诊时,右眼矫正视力手动,左眼矫正视力 20/25。裂隙灯检查显示右眼弥漫性中央基质浸润、瓣融化和前房积脓,左眼明显的界面混浊,边缘呈结晶状。行瓣掀起和冲洗术。由于角膜炎进行性加重,双眼行穿透性角膜移植术(PKP)。从两只角膜供体中均分离出木糖氧化无色杆菌,根据药敏试验结果,将治疗方案改为氯霉素泼尼松龙滴眼液,每日 8 次滴眼,静脉滴注美罗培南 500mg,每日 3 次。术后 2 个月,两次移植均保持透明。

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