Sahawneh Haitham F, Franco Jimena, Abusamak Mohammad, Bartley Jeremy
Department of Ophthalmology and Visual Sciences, Case Western Reserve University School of Medicine, Cleveland, USA.
Department of Ophthalmology, University Hospitals Eye Institute, University Hospitals Cleveland Medical Center, Cleveland, USA.
Cureus. 2024 Dec 10;16(12):e75472. doi: 10.7759/cureus.75472. eCollection 2024 Dec.
An 83-year-old male with a history of radial keratotomy and laser-assisted in situ keratomileusis (LASIK) presented with symptoms of a non-resolving corneal ulcer in the right eye that had been present for five months. The patient was treated with antibacterial, antiviral, and antifungal medications over that period, with multiple recurrences that prompted referral to our tertiary center for management. Following a 48-hour cessation of all medications, a corneal biopsy was performed which grew . In conclusion, remains a rare cause of keratitis but should be considered in patients with a slow-progressing disease. Risk factors include previous corneal surgeries or trauma, topical steroid use, and contact lens wear. Because grows slowly, it can have a deep impact on the cornea. To help antibiotics get into the cornea properly, epithelial debridement may be helpful. It does not respond to standard empiric antibiotic therapy. Ceftazidime and fourth-generation fluoroquinolones are better choices for treatment.
一名83岁男性,有放射状角膜切开术和准分子原位角膜磨镶术(LASIK)病史,右眼出现持续5个月未愈的角膜溃疡症状。在此期间,患者接受了抗菌、抗病毒和抗真菌药物治疗,多次复发促使其转诊至我们的三级中心进行处理。在停用所有药物48小时后,进行了角膜活检,培养出……。总之,……仍然是角膜炎的罕见病因,但对于病情进展缓慢的患者应予以考虑。危险因素包括既往角膜手术或外伤、局部使用类固醇以及佩戴隐形眼镜。由于……生长缓慢,它可对角膜产生严重影响。为帮助抗生素更好地进入角膜,上皮清创术可能会有帮助。它对标准经验性抗生素治疗无反应。头孢他啶和第四代氟喹诺酮类药物是更好的治疗选择。