Nozawa Keijirou, Watanabe Toshiaki
Dept. of Surgery, Teikyo University, Itabashi-ku, Tokyo, Japan.
Gan To Kagaku Ryoho. 2010 May;37(5):791-4.
For the patient in whom the Kras gene variation appears, cancer cell grow and continue to multiply even if blocked by EGFR inhibitor. A topping the offered figure effect of cetuximab is not accepted. The addition of cetuximab for treatment of metastatic colorectal cancer with Kras wild-type tumors is effective.
对于出现Kras基因变异的患者，即使被表皮生长因子受体（EGFR）抑制剂阻断，癌细胞仍会生长并持续增殖。西妥昔单抗的疗效未超过所提供的数据。对于Kras基因野生型肿瘤的转移性结直肠癌患者，添加西妥昔单抗进行治疗是有效的。
