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胰十二指肠损伤:重新评估当前的治疗方法。

Pancreaticoduodenal injuries: re-evaluating current management approaches.

作者信息

Chinnery G E, Madiba T E

机构信息

Department of Surgery, King Edward VIII Hospital, University of KwaZulu-Natal, Durban.

出版信息

S Afr J Surg. 2010 Feb;48(1):10-4.

Abstract

BACKGROUND

Pancreaticoduodenal injuries are uncommon owing to the protected position of the pancreas and duodenum in the retroperitoneum. Management depends on the extent of injury. This study was undertaken to document outcome of pancreaticoduodenal injuries and to re-evaluate our approach.

PATIENTS AND METHODS

A prospective study of all patients treated for pancreaticoduodenal trauma in one surgical ward at King Edward VIII hospital over a 7-year period (1998 - 2004). Demographic data, clinical presentation, findings at laparotomy and outcome were documented. Prophylactic antibiotics were given at induction of anaesthesia.

RESULTS

A total of 488 patients underwent laparotomy over this period, 43 (9%) of whom (all males) had pancreatic and duodenal injuries. Injury mechanisms were gunshot (30), stabbing (10) and blunt trauma (3). Their mean age was 30.1+9.6 years. Delay before laparotomy was 12.8+29.1 hours. Seven were admitted in shock. Mean Injury Severity Score (ISS) was 14+8.6. Management of 20 duodenal injuries was primary repair (14), repair and pyloric exclusion (3) and conservative (3). Management of 15 pancreatic injuries was drainage alone (13), conservative management of pseudocyst (1) and distal pancreatectomy (1). Management of 8 combined pancreaticoduodenal injuries was primary duodenal repair and pancreatic drainage (5) and repair with pyloric exclusion of duodenal injury and pancreatic drainage (3). Twenty-one patients (49%) developed complications, and 28 required ICU admission with a median ICU stay of 4 days. Ten patients died (23%). Mean hospital stay was 18.3+24.4 days.

CONCLUSIONS

The overall mortality was comparable with that in the world literature. We still recommend adequate exploration of the pancreas and duodenum and conservative operative management where possible.

摘要

背景

由于胰腺和十二指肠位于腹膜后位,受到保护,胰十二指肠损伤并不常见。治疗方法取决于损伤的程度。本研究旨在记录胰十二指肠损伤的治疗结果,并重新评估我们的治疗方法。

患者与方法

对1998年至2004年期间在爱德华八世国王医院一个外科病房接受胰十二指肠创伤治疗的所有患者进行前瞻性研究。记录人口统计学数据、临床表现、剖腹探查结果及治疗结果。麻醉诱导时给予预防性抗生素。

结果

在此期间,共有488例患者接受了剖腹探查,其中43例(9%)(均为男性)有胰腺和十二指肠损伤。损伤机制包括枪伤(30例)、刺伤(10例)和钝性创伤(3例)。他们的平均年龄为30.1±9.6岁。剖腹探查前的延迟时间为12.8±29.1小时。7例患者入院时处于休克状态。平均损伤严重程度评分(ISS)为14±8.6。20例十二指肠损伤的治疗方法为一期修复(14例)、修复加幽门旷置(3例)和保守治疗(3例)。15例胰腺损伤的治疗方法为单纯引流(13例)、假性囊肿保守治疗(1例)和胰体尾切除术(1例)。8例胰十二指肠联合损伤的治疗方法为十二指肠一期修复加胰腺引流(5例)以及十二指肠损伤修复加幽门旷置和胰腺引流(3例)。21例患者(49%)出现并发症,28例患者需要入住重症监护病房,重症监护病房的中位住院时间为4天。10例患者死亡(23%)。平均住院时间为18.3±24.4天。

结论

总体死亡率与世界文献报道相当。我们仍然建议对胰腺和十二指肠进行充分探查,并尽可能采用保守的手术治疗方法。

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