文献检索文档翻译深度研究
Suppr Zotero 插件Zotero 插件
邀请有礼套餐&价格历史记录

新学期，新优惠

限时优惠:9月1日-9月22日

30天高级会员仅需29元

1天体验卡首发特惠仅需5.99元

了解详情
不再提醒
插件&应用
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
高级版
套餐订阅购买积分包
AI 工具
文献检索文档翻译深度研究
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2025

德国一所大学医院临床分离的铜绿假单胞菌中金属β-内酰胺酶的首次调查。

First survey of metallo-beta-lactamases in clinical isolates of Pseudomonas aeruginosa in a German university hospital.

机构信息

Institute of Hygiene and Microbiology, University of Würzburg, Josef-Schneider-Str. 2/E1, 97080 Würzburg, Germany.

出版信息

Antimicrob Agents Chemother. 2010 Aug;54(8):3493-7. doi: 10.1128/AAC.00080-10. Epub 2010 May 24.

DOI:10.1128/AAC.00080-10
PMID:20498315
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2916321/
Abstract

A total of 489 clinical isolates of Pseudomonas aeruginosa was investigated for metallo-beta-lactamase (MBL) production. Molecular analysis detected a blaVIM-1 gene in the chromosome of one isolate and a blaVIM-2 gene carried on the plasmid in seven isolates. Moreover, we showed that an initial screening by combined susceptibility testing of imipenem and ceftazidime followed by a confirmatory EDTA combination disk test represents a valid alternative to the molecular investigation of MBL genes, making MBL detection possible in routine diagnostic laboratories.

摘要

共研究了 489 株铜绿假单胞菌临床分离株的金属β-内酰胺酶（MBL）产生情况。分子分析在一株菌的染色体中检测到 blaVIM-1 基因，在七株菌的质粒中检测到 blaVIM-2 基因。此外，我们还表明，采用亚胺培南和头孢他啶联合药敏试验进行初始筛选，然后进行 EDTA 联合纸片确证试验，是 MBL 基因分子检测的有效替代方法，可在常规诊断实验室中进行 MBL 检测。

相似文献

[1]
First survey of metallo-beta-lactamases in clinical isolates of Pseudomonas aeruginosa in a German university hospital.

Antimicrob Agents Chemother. 2010-5-24

[2]
Dissemination of Pseudomonas aeruginosa producing SPM-1-like and IMP-1-like metallo-beta-lactamases in hospitals from southern Brazil.

Infection. 2007-12

[3]
Study of metallo-beta-lactamase production in clinical isolates of Pseudomonas aeruginosa.

Indian J Med Microbiol. 2008

[4]
Prevalence of metallo-beta-lactamase among Pseudomonas aeruginosa and Acinetobacter baumannii in a Korean university hospital and comparison of screening methods for detecting metallo-beta-lactamase.

J Microbiol Methods. 2003-9

[5]
[Molecular epidemiology of beta-lactamases in ceftazidime-resistant Pseudomonas aeruginosa isolates].

Mikrobiyol Bul. 2015-4

[6]
Identification and genetic characterization of metallo-beta-lactamase-producing strains of Pseudomonas aeruginosa in Tehran, Iran.

New Microbiol. 2010-7

[7]
Predominance of carbapenem-resistant Pseudomonas aeruginosa isolates carrying blaIMP and blaVIM metallo-β-lactamases in a major hospital in Costa Rica.

J Med Microbiol. 2015-1

[8]
Diversity of β-lactamases produced by imipenem resistant, Pseudomonas aeruginosa isolates from the bloodstream.

Burns. 2014-11

[9]
Molecular epidemiology of clinical Pseudomonas aeruginosa isolates carrying IMP-1 metallo-beta-lactamase gene in a University Hospital in Turkey.

Microb Drug Resist. 2007

[10]
Spread of efflux pump-overexpressing, non-metallo-beta-lactamase-producing, meropenem-resistant but ceftazidime-susceptible Pseudomonas aeruginosa in a region with blaVIM endemicity.

J Antimicrob Chemother. 2005-10

引用本文的文献

[1]
Evaluation of matrix-assisted laser desorption/ionization time-of-flight mass spectrometry for identifying VIM- and SPM-type metallo-β-lactamase-producing clinical isolates.

Infect Drug Resist. 2019-9-6

[2]
Prevalence of Clinically Isolated Metallo-beta-lactamase-producing , Coding Genes, and Possible Risk Factors in Iran.

Iran J Pathol. 2018

[3]
Prevalence and Clonal Dissemination of Metallo-Beta-Lactamase-Producing Pseudomonas aeruginosa in Kermanshah.

Jundishapur J Microbiol. 2015-7-27

[4]
Epidemiology and Characteristics of Metallo-β-Lactamase-Producing Pseudomonas aeruginosa.

Infect Chemother. 2015-6

[5]
Dissemination of IMP-6-producing Pseudomonas aeruginosa ST244 in multiple cities in China.

Eur J Clin Microbiol Infect Dis. 2014-7

[6]
Effect of metallo-β-lactamase production and multidrug resistance on clinical outcomes in patients with Pseudomonas aeruginosa bloodstream infection: a retrospective cohort study.

BMC Infect Dis. 2013-11-1

[7]
β -Lactamase-Producing Multidrug-Resistant Bacterial Pathogens from Tracheal Aspirates of Intensive Care Unit Patients at National Institute of Neurological and Allied Sciences, Nepal.

ISRN Microbiol. 2013-9-2

[8]
Identification and characterization of metallo-β-lactamases producing Pseudomonas aeruginosa clinical isolates in University Hospital from Zanjan Province, Iran.

Iran Biomed J. 2013

本文引用的文献

[1]
Characterization of DIM-1, an integron-encoded metallo-beta-lactamase from a Pseudomonas stutzeri clinical isolate in the Netherlands.

Antimicrob Agents Chemother. 2010-3-22

[2]
Nosocomial outbreak of VIM-2 metallo-β-lactamase-producing Pseudomonas aeruginosa associated with retrograde urography.

Clin Microbiol Infect. 2010-9

[3]
Antibacterial-resistant Pseudomonas aeruginosa: clinical impact and complex regulation of chromosomally encoded resistance mechanisms.

Clin Microbiol Rev. 2009-10

[4]
Characterization of a new metallo-beta-lactamase gene, bla(NDM-1), and a novel erythromycin esterase gene carried on a unique genetic structure in Klebsiella pneumoniae sequence type 14 from India.

Antimicrob Agents Chemother. 2009-9-21

[5]
Metallo-beta-lactamase-producing Pseudomonas spp. in Korea: high prevalence of isolates with VIM-2 type and emergence of isolates with IMP-1 type.

Yonsei Med J. 2009-6-30

[6]
First countrywide survey of acquired metallo-beta-lactamases in gram-negative pathogens in Italy.

Antimicrob Agents Chemother. 2008-11

[7]
VIM-15 and VIM-16, two new VIM-2-like metallo-beta-lactamases in Pseudomonas aeruginosa isolates from Bulgaria and Germany.

Antimicrob Agents Chemother. 2008-8

[8]
New and sensitive assay for determining Pseudomonas aeruginosa metallo-beta-lactamase resistance to imipenem.

J Clin Microbiol. 2008-5

[9]
Evaluation of phenotypic tests for the detection of metallo-beta-lactamase-producing Pseudomonas aeruginosa in a low prevalence country.

J Antimicrob Chemother. 2008-4

[10]
Molecular epidemiology of clinical Pseudomonas aeruginosa isolates carrying IMP-1 metallo-beta-lactamase gene in a University Hospital in Turkey.

Microb Drug Resist. 2007

文献AI研究员

20分钟写一篇综述，助力文献阅读效率提升50倍

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

推荐工具

医学文档翻译智能文献检索