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具有治愈潜力的转移性结直肠癌的手术治疗。

Surgical therapies in metastatic colorectal cancer with a potential for cure.

机构信息

Department of Surgery, St George Hospital, Sydney, Australia.

出版信息

Am J Clin Oncol. 2011 Jun;34(3):326-31. doi: 10.1097/COC.0b013e3181dbb9ad.

DOI:10.1097/COC.0b013e3181dbb9ad
PMID:20498587
Abstract

Metastatic colorectal cancer has evolved from a paradigm that was previously centered upon the use of systemic chemotherapy to one of multimodality therapy. Hepatectomy, pulmonary metastasectomy, and cytoreductive surgery with hyperthermic intraperitoneal chemotherapy are surgical procedures that are now routinely performed in specialized institutions treating patients with metastatic colorectal cancer. Emerging evidence suggests that in selected patients, these procedures are safe and may be beneficial in contributing to long-term survival.

摘要

转移性结直肠癌已从以前以全身化疗为中心的模式演变为多模式治疗。肝切除术、肺转移瘤切除术和细胞减灭术联合腹腔内热化疗是目前在专门治疗转移性结直肠癌患者的机构中常规进行的手术。新出现的证据表明,在某些选定的患者中,这些手术是安全的,并且可能有助于长期生存。

相似文献

1
Surgical therapies in metastatic colorectal cancer with a potential for cure.具有治愈潜力的转移性结直肠癌的手术治疗。
Am J Clin Oncol. 2011 Jun;34(3):326-31. doi: 10.1097/COC.0b013e3181dbb9ad.
2
Long-term outcome of initially unresectable metastatic colorectal cancer patients treated with 5-fluorouracil/leucovorin, oxaliplatin, and irinotecan (FOLFOXIRI) followed by radical surgery of metastases.初始不可切除的转移性结直肠癌患者接受氟尿嘧啶/亚叶酸钙、奥沙利铂和伊立替康(FOLFOXIRI)治疗后行转移灶根治性手术的长期预后。
Ann Surg. 2009 Mar;249(3):420-5. doi: 10.1097/SLA.0b013e31819a0486.
3
Metastatic colorectal cancer: is surgery necessary?转移性结直肠癌:手术是否必要?
J Natl Cancer Inst. 2009 Aug 19;101(16):1113-5. doi: 10.1093/jnci/djp269. Epub 2009 Aug 11.
4
Long-term outcome of unresectable metastatic colorectal cancer: does "adjuvant" chemotherapy play a role after resection?不可切除转移性结直肠癌的长期预后:“辅助”化疗在切除术后是否起作用?
Ann Surg. 2009 Oct;250(4):654-5; author reply 655. doi: 10.1097/SLA.0b013e3181b97e98.
5
[A case of resection of synchronous multiple liver metastases from colorectal cancer after hepatic infusion chemotherapy and systemic chemotherapy].[1例经肝动脉灌注化疗及全身化疗后切除结直肠癌同期多发肝转移灶的病例]
Gan To Kagaku Ryoho. 2007 Sep;34(9):1481-4.
6
[Specific treatment situations in metastatic colorectal cancer].[转移性结直肠癌的特定治疗情况]
Onkologie. 2010;33 Suppl 4:8-18. doi: 10.1159/000308447. Epub 2010 Apr 23.
7
[Prehepatectomy chemotherapy using hepatic artery infusion plus systemic chemotherapy for liver metastases from colorectal cancer].[采用肝动脉灌注联合全身化疗的肝切除术前化疗治疗结直肠癌肝转移]
Gan To Kagaku Ryoho. 2010 Nov;37(12):2267-70.
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[Treatment of peritoneal carcinomatosis from colorectal and appendiceal cancer by extensive cytoreductive surgery combined with hyperthermic intraoperative intraperitoneal chemotherapy].[通过广泛的细胞减灭术联合术中腹腔内热化疗治疗结直肠癌和阑尾癌所致的腹膜癌病]
Rev Med Brux. 2005 Sep-Oct;26(5):439-44.
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Evolution of systemic therapy for metastatic colorectal cancer.转移性结直肠癌全身治疗的进展
Colorectal Dis. 2011 Aug;13(8):852-4. doi: 10.1111/j.1463-1318.2011.02710.x.
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Unresectable hepatic colorectal metastases: need for new surgical strategies.不可切除的肝结肠转移瘤:对新手术策略的需求
Ann Surg Oncol. 2006 Jan;13(1):5-6. doi: 10.1245/ASO.2006.08.938. Epub 2006 Jan 1.

引用本文的文献

1
Synchronous liver and peritoneal metastases from colorectal cancer: Is cytoreductive surgery and hyperthermic intraperitoneal chemotherapy combined with liver resection a feasible option?结直肠癌的同步肝转移和腹膜转移:细胞减灭术及腹腔内热化疗联合肝切除是否为可行的选择?
Front Surg. 2022 Dec 15;9:1006591. doi: 10.3389/fsurg.2022.1006591. eCollection 2022.
2
Survival time and prognostic factors of patients with initial noncurative colorectal liver metastases.初治不可切除结直肠癌肝转移患者的生存时间及预后因素
Medicine (Baltimore). 2017 Dec;96(51):e8831. doi: 10.1097/MD.0000000000008831.
3
Hepatic metastases of colorectal cancer are rather homogeneous but differ from primary lesions in terms of immune cell infiltration.
结直肠癌肝转移灶相当均匀一致,但在免疫细胞浸润方面与原发灶有所不同。
Oncoimmunology. 2013 Apr 1;2(4):e24116. doi: 10.4161/onci.24116.