Department of Urology, Yonsei University College of Medicine, Gangnam Severance Hospital, Gangnam-gu, Seoul, Korea.
Yonsei Med J. 2010 Jul;51(4):569-73. doi: 10.3349/ymj.2010.51.4.569.
Diagnosis and proper treatment of renal abscesses remains a challenge for physicians. We investigated the characteristics and comorbidity factors of renal abscesses measuring 5 cm or less and critically examined the effectiveness of conservative treatment.
Between February 2001 and March 2009 the records of 63 patients initially diagnosed at our hospital with renal or perirenal abscesses were retrospectively reviewed. In 63 patients with renal and perirenal abscesses, 51 abscesses measured 5 cm or less, and 49 abscesses were treated with intravenous antibiotics alone.
Most patients were women (91.8%), and their mean age was 42.3 years. The mean size of renal abscesses was 3.6 cm. The most common predisposing condition was diabetes mellitus (DM) (46.9%). Common clinical features were fever (83.7%) and flank pain (53.1%). On urinalysis, 31 (64.6%) cases had positive bacterial cultures with Escherichia coli (50.0%) being the most common pathogen. All 49 patients were treated with broad-spectrum intravenous antibiotics alone. All patients showed complete clinical regression and resolution of the renal lesions shown by CT between 3 and 14 weeks. The average hospital stay was 15.3 days (range, 5-31 days). Significant predictors of a long hospital stay were age, abscess size, and DM.
Medium-sized as well as small-sized renal abscesses were treated successfully with intravenous antibiotics alone. DM was a significant predictor of prolonged hospital stay. If therapeutic drainage is believed to involve considerable risk, then intravenous antimicrobial therapy may be a good alternative treatment.
肾脓肿的诊断和恰当治疗仍然是医师面临的挑战。我们研究了直径 5cm 或以下肾脓肿的特征和合并症因素,并深入研究了保守治疗的效果。
回顾性分析 2001 年 2 月至 2009 年 3 月期间我院最初诊断为肾脓肿或肾周脓肿的 63 例患者的记录。在 63 例肾脓肿和肾周脓肿患者中,51 个脓肿直径为 5cm 或以下,49 个脓肿仅采用静脉抗生素治疗。
大多数患者为女性(91.8%),平均年龄为 42.3 岁。肾脓肿的平均大小为 3.6cm。最常见的易患疾病是糖尿病(DM)(46.9%)。常见的临床特征是发热(83.7%)和腰痛(53.1%)。在尿分析中,31 例(64.6%)有阳性细菌培养,最常见的病原体是大肠杆菌(50.0%)。所有 49 例患者均仅采用广谱静脉抗生素治疗。所有患者在 3 至 14 周之间通过 CT 显示完全临床缓解和肾病变消退。平均住院时间为 15.3 天(5-31 天)。住院时间延长的显著预测因素是年龄、脓肿大小和 DM。
中、小肾脓肿单独采用静脉抗生素治疗即可获得成功。DM 是住院时间延长的显著预测因素。如果认为治疗性引流存在较大风险,那么静脉抗菌治疗可能是一种较好的替代治疗方法。