Norwegian Centre for Dementia Research, Centre for Ageing and Health, Department of Geriatric Medicine, Oslo University Hospital, Oslo, Norway. maria.barca @ aldringoghelse.no
Dement Geriatr Cogn Disord. 2010;29(5):438-47. doi: 10.1159/000313533. Epub 2010 May 25.
The validity of the Cornell Scale for Depression in Dementia is seldom studied in institutions.
Two reliability studies, with 103 and 32 patients, and a validity study with 231 patients in nursing homes and in hospital were performed. They were assessed by the Cornell Scale, Clinical Dementia Rating scale and Self-Maintenance scale. A psychiatrist 'blind' to the Cornell assessment diagnosed depression according to the ICD-10, DSM-IV-TR and the Provisional Criteria for Depression in Alzheimer's Disease (PCD-dAD).
Cronbach's alpha values were 0.81 and 0.95, and the mean kappa for the Cornell items were 0.91 and 0.57, respectively. In the validity study, 164 subjects had dementia; 105 (45.5%) had depression according to the ICD-10, 68 (29.9%) according to the DSM-IV-TR and 88 (53.3%) of the demented patients had depression according to the PCD-dAD. In the receiver operating characteristic analysis, the DSM-IV-TR criteria produced the highest area under the curve, i.e. 0.81 (95% CI: 0.75-0.87). A range of cutoff points for a depressive disorder was found for the various clinical criteria.
The Cornell Scale is reliable and a range of cutoff points should be used for various clinical criteria of depression.
康奈尔抑郁量表在医疗机构中的有效性很少得到研究。
对 103 例和 32 例患者进行了两项可靠性研究，对 231 例疗养院和医院患者进行了一项有效性研究。他们接受了康奈尔量表、临床痴呆评定量表和自我维持量表的评估。一位对康奈尔评估“盲”的精神科医生根据 ICD-10、DSM-IV-TR 和暂定阿尔茨海默病抑郁标准（PCD-dAD）诊断了抑郁症。
Cronbach's alpha 值分别为 0.81 和 0.95，康奈尔项目的平均kappa 值分别为 0.91 和 0.57。在有效性研究中，164 名受试者患有痴呆症；根据 ICD-10，105 名（45.5%）患有抑郁症，根据 DSM-IV-TR，68 名（29.9%）患有抑郁症，根据 PCD-dAD，88 名（53.3%）痴呆患者患有抑郁症。在受试者工作特征曲线分析中，DSM-IV-TR 标准产生的曲线下面积最高，即 0.81（95%CI：0.75-0.87）。发现了各种临床标准的抑郁障碍的截断点范围。
康奈尔量表具有可靠性，对于各种临床抑郁标准，应使用一系列截断点。
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