Rulo H F, van de Kerkhof P C
Department of Dermatology, University Hospital Nijmegen, The Netherlands.
Dermatologica. 1991;182(2):112-4. doi: 10.1159/000247756.
Inflammatory linear verrucous epidermal nevus (ILVEN) is a rare and chronic skin disorder, which may trouble the patient considerably. The condition is generally believed to be resistant to therapy, although some authors have reported success with several treatments. including dithranol and etretinate. The present case, a classical presentation of ILVEN, again illustrates the refractoriness to various treatments, including an experimental treatment with topical 13-cis-retinoic acid. A review of the literature on therapeutic possibilities of ILVEN is presented. Based on our own observations and literature data, it is attractive to hypothesize that a positive result with treatments such as dithranol and retinoids should be interpreted as an antipsoriatic effect in ILVEN with superimposed psoriasis.
炎症性线状疣状表皮痣（ILVEN）是一种罕见的慢性皮肤疾病，会给患者带来相当大的困扰。尽管一些作者报告了几种治疗方法取得的成功，包括地蒽酚和阿维A酯，但一般认为这种疾病对治疗有抗性。本病例是ILVEN的典型表现，再次说明了其对各种治疗方法的难治性，包括外用13 - 顺式维甲酸的实验性治疗。本文对ILVEN的治疗可能性相关文献进行了综述。基于我们自己的观察和文献数据，有吸引力的假设是，地蒽酚和维甲酸类等治疗方法的阳性结果应被解释为ILVEN合并银屑病时的抗银屑病作用。
