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在不符合血管内动脉瘤修复条件的患有严重慢性阻塞性肺疾病的清醒患者中,联合脊髓和硬膜外麻醉用于开放性腹主动脉瘤手术。结果分析与技术描述。

Combined spinal and epidural anesthesia for open abdominal aortic aneurysm surgery in vigil patients with severe chronic obstructive pulmonary disease ineligible for endovascular aneurysm repair. Analysis of results and description of the technique.

作者信息

Berardi G, Ferrero E, Fadde M, Lojacono N, Ferri M, Viazzo A, Gaggiano A, Bianchi A, Maggio D, Ganzaroli M, Piazza S, Cumbo P, Lamorgese V, Verdecchia C, Nessi F

机构信息

Department of Cardiac and Vascular Disease, Vascular and Endovascular Surgery Unit, Mauriziano Umberto I Hospital, Turin, Italy.

出版信息

Int Angiol. 2010 Jun;29(3):278-83.

Abstract

This study evaluated the feasibility of open infrarenal abdominal aortic aneurysm (AAA) surgery under peridural and spinal anesthesia (vigil patient) alone in high-risk patients with severe chronic obstructive pulmonary disease (COPD) ineligible for endovascular aneurysm repair (EVAR) or open surgery in general anesthesia. Between January 2005 and July 2007, seven patients underwent open AAA surgery with combined spinal and epidural anesthesia ([CSEA] without intubation) alone. Regional abdominal anesthesia was established by spinal anesthesia at L2-3 (levobupivacaine plus fentanyl) associated with peridural anesthesia at T7-8 (levobupivacaine). In this series (6 males and 1 female) the average age was 76.5 years (70-87); the AAA measured 7 cm in diameter on average (range 6-12.2). The survival rate was 100% (7/7 patients) at 6-12 months postoperative; no morbidities occurred during the postoperative phase. Owing to the small size of the series, no statistically significant conclusions can be drawn; even so, repair surgery was found to be effective, without the occurrence of morbidities or mortalities. In high-risk patients (severe COPD), open surgical repair of infrarenal AAA may be done with CSEA alone without intubation when, because of the patient's health, general anesthesia would pose too high a risk or when EVAR is unfeasible. Furthermore, the authors believe that surgical AAA repair under CSEA in vigil patients is a valid treatment option in those subjects with a high operative risk (severe COPD) and untreatable by either open AAA surgery under general anesthesia or EVAR.

摘要

本研究评估了对于因患有严重慢性阻塞性肺疾病(COPD)而具有高手术风险、不符合血管腔内动脉瘤修复术(EVAR)或无法接受全身麻醉下开放手术的患者,仅在硬膜外和脊髓麻醉(清醒患者)下进行开放性肾下腹主动脉瘤(AAA)手术的可行性。在2005年1月至2007年7月期间,7例患者仅接受了腰麻联合硬膜外麻醉([CSEA],不插管)下的开放性AAA手术。通过L2 - 3椎间隙脊髓麻醉(左旋布比卡因加芬太尼)联合T7 - 8椎间隙硬膜外麻醉(左旋布比卡因)建立区域腹部麻醉。在该系列患者中(6例男性和1例女性),平均年龄为76.5岁(70 - 87岁);AAA平均直径为7 cm(范围6 - 12.2 cm)。术后6 - 12个月生存率为100%(7/7例患者);术后阶段未发生任何并发症。由于该系列样本量较小,无法得出具有统计学意义的结论;即便如此,发现修复手术是有效的,未出现并发症或死亡情况。对于高风险患者(严重COPD),当因患者健康状况全身麻醉风险过高或EVAR不可行时,单纯采用CSEA不插管进行肾下AAA开放手术修复是可行的。此外,作者认为,对于手术风险高(严重COPD)且无法通过全身麻醉下开放AAA手术或EVAR治疗的患者,在清醒患者中采用CSEA进行AAA手术修复是一种有效的治疗选择。

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