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内镜下第三脑室造瘘术翻修术的回顾性分析

A retrospective analysis of revision endoscopic third ventriculostomy.

作者信息

Surash Surash, Chumas Paul, Bhargava Deepti, Crimmins Darach, Straiton John, Tyagi Atul

机构信息

Department of Neurosurgery, The General Infirmary at Leeds, Great George Street, Leeds, West Yorkshire, LS1 3EX, UK.

出版信息

Childs Nerv Syst. 2010 Dec;26(12):1693-8. doi: 10.1007/s00381-010-1176-0. Epub 2010 May 26.

Abstract

PURPOSE

Endoscopic third ventriculostomy (ETV) has gained favour as an effective treatment for obstructive hydrocephalus. However, the timing of ETV failure and the long-term efficacy of revision ETV remain poorly documented.

METHODS

A retrospective review was performed of patients undergoing revision ETV between 1999 and 2007. Only those patients in whom there was evidence of a good sustained clinical improvement after the initial ETV were considered candidates for ETV revision. All other patients underwent insertion of a ventriculoperitoneal shunt at the time of ETV failure. Failures that were selected for repeat ETV were subdivided into; "early" if the revision occurred within the first 3 months of the primary procedure and "late" if occurring after this.

RESULTS

Ten patients underwent revision ETV (6% of all ETVs performed). Age ranged from 2 months to 32 years (mean 13.6 years). Three "early" revision ETV were performed at a mean of 1.3 months, and there were seven "late" revisions performed at a mean of 27 months. The stoma was closed in seven patients and narrowed in one patient, and a second membrane was found under the original patent stoma in a further two patients. In two patients, a third ETV procedure was performed (both at 1 month after second ETV), and the stoma was closed in both these patients. No patients have required a shunt.

CONCLUSION

At last follow-up (mean 38 months), all patients remain well. Revision ETV appears a safe and effective means of managing hydrocephalus-providing there is clinical evidence that the primary procedure was initially effective. It is important to emphasise that patients with an initially successful ETV are by no means "cured".

摘要

目的

内镜下第三脑室造瘘术(ETV)已成为治疗梗阻性脑积水的有效方法。然而,ETV失败的时间以及翻修ETV的长期疗效仍缺乏充分记录。

方法

对1999年至2007年间接受翻修ETV的患者进行回顾性研究。仅将那些在初次ETV后有持续良好临床改善证据的患者视为ETV翻修的候选者。所有其他患者在ETV失败时接受脑室腹腔分流术。被选进行重复ETV的失败病例分为:如果翻修在初次手术的前3个月内进行则为“早期”,如果在此之后进行则为“晚期”。

结果

10例患者接受了翻修ETV(占所有ETV手术的6%)。年龄范围为2个月至32岁(平均13.6岁)。3例“早期”翻修ETV平均在1.3个月时进行,7例“晚期”翻修平均在27个月时进行。7例患者的造瘘口闭合,1例患者的造瘘口变窄,另外2例患者在原来通畅的造瘘口下方发现了第二层膜。2例患者进行了第三次ETV手术(均在第二次ETV后1个月),这2例患者的造瘘口均闭合。没有患者需要分流。

结论

在最后一次随访时(平均38个月),所有患者情况良好。翻修ETV似乎是治疗脑积水的一种安全有效的方法——前提是有临床证据表明初次手术最初是有效的。需要强调的是,初次ETV成功的患者绝非“治愈”。

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