Netto D, Shah I A
Laboratory Service, Veterans Affairs Medical Center, Dallas, TX 85012.
Hum Pathol. 1991 Apr;22(4):398-401. doi: 10.1016/0046-8177(91)90089-8.
We report on the rare association of Hodgkin's disease with systemic lupus erythematosus. Two years after the diagnosis of systemic lupus erythematosus, the patient developed upper abdominal pain, jaundice, splenomegaly, and fever of unknown origin. He had a rapidly fatal clinical course, despite being treated for systemic lupus erythematosus, cholecystitis, and possible sepsis. Autopsy revealed Hodgkin's disease, lymphocyte-depletion type, involving lymph nodes, liver, spleen, and bone marrow. The awareness of the association of Hodgkin's disease with systemic lupus erythematosus and its modes of presentation will help in the early diagnosis and management of such patients.
我们报告了霍奇金病与系统性红斑狼疮的罕见关联。在诊断为系统性红斑狼疮两年后，患者出现上腹部疼痛、黄疸、脾肿大及不明原因发热。尽管接受了系统性红斑狼疮、胆囊炎及可能的败血症治疗，但其临床病程迅速恶化，最终死亡。尸检发现为淋巴细胞消减型霍奇金病，累及淋巴结、肝脏、脾脏及骨髓。认识到霍奇金病与系统性红斑狼疮的关联及其表现形式，将有助于对此类患者进行早期诊断和治疗。
