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疼痛与抑郁并存预示着腰椎管狭窄症患者两年手术效果不佳。

Coexistence of pain and depression predicts poor 2-year surgery outcome among lumbar spinal stenosis patients.

作者信息

Sinikallio Sanna, Airaksinen Olavi, Aalto Timo, Lehto Soili M, Kröger Heikki, Viinamäki Heimo

机构信息

Department of Rehabilitation, Kuopio University Hospital, Kuopio, Finland.

出版信息

Nord J Psychiatry. 2010 Dec;64(6):391-6. doi: 10.3109/08039481003759193. Epub 2010 May 27.

Abstract

BACKGROUND

Lumbar spinal stenosis is a common cause of back and leg pain with the most severe cases treated surgically. Regarding the surgery outcome, the importance of early postoperative depression and pain is unknown.

AIMS

To examine whether the coexistence of pain and depressive symptoms on 3-month follow-up predicts the 2-year surgery outcome.

METHODS

93 patients (mean age 62 years) with symptomatic lumbar spinal stenosis underwent decompressive surgery. They completed the same set of questionnaires, 3 months, 1 year and 2 years postoperatively. Depression was assessed with the 21-item Beck Depression Inventory (BDI). Physical functioning and pain were assessed with the Oswestry Disability Index, the Stucki Questionnaire, self-reported walking ability, the visual analogue scale (VAS) and pain drawing. Comparisons were made between groups according to the "misery" (i.e. the coexistence of elevated pain and depression on 3-month follow-up) status. Logistic regression analysis was used to examine the factors independently associated with a poor surgery outcome on 2-year follow-up.

RESULTS

The patients in the misery group (n=24) showed greater symptom severity and greater disability than the patients in the non-misery group (n=69) at all follow-up stages. No clinical improvement was seen in the misery group during the follow-up. An independent association was observed between belonging to the misery group and 2-year disability, symptom severity and poor walking capacity.

CONCLUSIONS

Even moderately increased VAS and BDI scores, when presenting simultaneously on an individual patient level during the early postoperative period, imply a strong clinical burden and a risk factor for poor recovery. The assessment of pain and depressive symptoms is encouraged.

摘要

背景

腰椎管狭窄症是导致腰腿痛的常见原因,最严重的病例需手术治疗。关于手术效果,术后早期抑郁和疼痛的重要性尚不清楚。

目的

探讨术后3个月随访时疼痛与抑郁症状并存是否可预测2年手术效果。

方法

93例有症状的腰椎管狭窄症患者(平均年龄62岁)接受了减压手术。他们在术后3个月、1年和2年完成了同一组问卷调查。使用21项贝克抑郁量表(BDI)评估抑郁情况。使用奥斯威斯利残疾指数、斯图基问卷、自我报告的步行能力、视觉模拟量表(VAS)和疼痛图评估身体功能和疼痛情况。根据“痛苦”(即术后3个月随访时疼痛加剧与抑郁并存)状态对组间进行比较。采用逻辑回归分析来检验与2年随访时手术效果不佳独立相关的因素。

结果

在所有随访阶段,“痛苦”组(n = 24)的患者比“非痛苦”组(n = 69)的患者症状更严重,残疾程度更高。随访期间,“痛苦”组未见临床改善。“痛苦”组与2年残疾、症状严重程度和步行能力差之间存在独立关联。

结论

即使术后早期个体患者的VAS和BDI评分适度升高,同时出现也意味着临床负担较重且恢复不良的风险因素。鼓励对疼痛和抑郁症状进行评估。

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