Luttke A
Int J Biomed Comput. 1991 Mar-Apr;27(3-4):193-200. doi: 10.1016/0020-7101(91)90062-j.
REPLI, a program written in elementary BASIC, calculates the approximate sample size, which is required to detect a desired difference between any two group means in an experiment with n groups for a given probability and at three significance levels of the means difference. A prior knowledge of the variability of data in the groups is expected in order to base the estimate on a rational footing. If this knowledge does not exist, an educated guess and/or several trials with different assumptions on the most likely variability can be used. The a priori estimate prevents that sample sizes are completely out of a reasonable range. Since the program is applicable for experimental settings where several groups need be investigated, it is particularly interesting to users of ANOVA and/or comparable non-parametric tests.
REPLI是一个用基本BASIC语言编写的程序，它可以计算出近似样本量。在一个有n个组的实验中，对于给定的概率以及均值差异的三个显著性水平，要检测任意两组均值之间的期望差异，就需要这个近似样本量。为了使估计基于合理的基础，需要事先了解各组数据的变异性。如果不存在这种了解，可以进行有根据的猜测和/或对最可能的变异性进行几种不同假设的试验。先验估计可防止样本量完全超出合理范围。由于该程序适用于需要研究多个组的实验设置，因此对于方差分析和/或类似非参数检验的用户来说特别有意义。
