Cadogan Mary P
University of California, Los Angeles, School of Nursing, Los Angeles, CA, USA.
J Gerontol Nurs. 2010 Jun;36(6):16-21. doi: 10.3928/00989134-20100504-08. Epub 2010 Jun 4.
Vitamin B(12) deficiency is a common but underrecognized problem in older adults. Historically, B(12) deficiency was diagnosed once a severe pernicious anemia developed. Scientific developments have led to a new understanding of a broader spectrum of B(12) deficiency and identification of a milder form of deficiency associated with food/vitamin B(12) malabsorption. Using an individual example, this article describes the functional impact of vitamin B(12) deficiency and highlights modern approaches to diagnosis and treatment.
维生素B12缺乏在老年人中是一个常见但未得到充分认识的问题。从历史上看,一旦出现严重的恶性贫血,才会诊断出维生素B12缺乏。科学的发展使人们对更广泛的维生素B12缺乏有了新的认识,并识别出一种与食物/维生素B12吸收不良相关的较轻形式的缺乏。本文通过一个具体例子,描述了维生素B12缺乏的功能影响,并重点介绍了现代的诊断和治疗方法。