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微剂量学测量描绘了在水中停止的 300 MeV/u 12C 和 185 MeV/u 7Li 笔形束的辐射场。

Microdosimetry measurements characterizing the radiation fields of 300 MeV/u 12C and 185 MeV/u 7Li pencil beams stopping in water.

机构信息

GSI Helmholtzzentrum für Schwerionenforschung GmbH, 64291 Darmstadt, Germany.

出版信息

Phys Med Biol. 2010 Jun 21;55(12):3441-9. doi: 10.1088/0031-9155/55/12/011. Epub 2010 May 28.

DOI:10.1088/0031-9155/55/12/011
PMID:20508316
Abstract

In order to characterize the complex radiation field produced by heavy-ion beams in water, in particular the lateral dose fall-off and the radiation quality, microdosimetry measurements were performed at GSI Darmstadt using pencil-like beams of 300 MeV/u (12)C and 185 MeV/u (7)Li ions delivered by the heavy-ion synchrotron SIS-18. The ion beams (range in water about 17 cm) were stopped in the center of a 30 x 30 x 30 cm(3) water phantom and their radiation field was investigated by in-phantom measurements using a tissue-equivalent proportional chamber (TEPC). The chamber was placed at 35 different positions in the central plane at various depths along the beam axis and at radial distances of 0, 1, 2, 5 and 10 cm. The off-axis measurements for both (12)C and (7)Li ions show very similar distributions of the lineal energy, all peaking between 1 and 10 keV microm(-1) which is a typical range covered by secondary hydrogen fragments and neutrons. The radiation quality given by the dose-mean lineal energy [Formula in text] was found to be at a constant level of 1-2 keV microm(-1) at radial distances larger than 2 cm. The relative absorbed dose at each position was obtained by integration of the measured spectra normalized to the number of incident primary beam particles. The results confirm that the lateral dose profile of heavy ions shows an extremely steep fall-off, with relative values of about 10(-3), 10(-4) and 10(-5) at the 2, 5 and 10 cm distance from the beam axis, respectively. The depth-dose curves at a fixed distance from the beam axis slowly rise until they reach the depth of the Bragg peak, reflecting the build-up of secondary fragments with increasing penetration depth. The measured (12)C dose profiles were found to be in good agreement with a similar experimental study at HIMAC (Japan).

摘要

为了描述重离子束在水中产生的复杂辐射场,特别是侧向剂量下降和辐射品质,我们在达姆施塔特的 GSI 使用铅笔状的 300 MeV/u(12)C 和 185 MeV/u(7)Li 离子束进行了微剂量学测量,这些离子束由重离子同步加速器 SIS-18 提供。离子束(在水中的射程约为 17 厘米)在一个 30 x 30 x 30 立方厘米的水模体的中心停止,它们的辐射场通过使用组织等效比例室(TEPC)在体模内进行测量来研究。该室放置在中心平面的 35 个不同位置,沿着束轴的不同深度和径向距离为 0、1、2、5 和 10 厘米。对于(12)C 和(7)Li 离子的离轴测量都显示出线性能量分布非常相似,所有分布都在 1 到 10 keV μm(-1)之间达到峰值,这是二次氢碎片和中子的典型覆盖范围。由剂量平均线性能量[公式文字]给出的辐射品质在大于 2 厘米的径向距离处保持在 1-2 keV μm(-1)的恒定水平。通过将测量的谱图积分并归一化为入射初级束粒子的数量,获得每个位置的相对吸收剂量。结果证实,重离子的侧向剂量分布显示出极其陡峭的下降,在离束轴 2、5 和 10 厘米的距离处,相对值分别约为 10(-3)、10(-4)和 10(-5)。在固定距离处从束轴的深度剂量曲线缓慢上升,直到达到布拉格峰的深度,这反映了随着穿透深度的增加,二次碎片的积累。测量的(12)C 剂量分布与 HIMAC(日本)的类似实验研究结果吻合良好。

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