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Beneficial effects of combining a type II ATP competitive inhibitor with an allosteric competitive inhibitor of BCR-ABL for the treatment of imatinib-sensitive and imatinib-resistant CML.

作者信息

Weisberg E, Deng X, Choi H G, Barrett R, Adamia S, Ray A, Moreno D, Kung A L, Gray N, Griffin J D

出版信息

Leukemia. 2010 Jul;24(7):1375-8. doi: 10.1038/leu.2010.107. Epub 2010 May 27.

Abstract
摘要

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Targeting Bcr-Abl by combining allosteric with ATP-binding-site inhibitors.
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Crystal structure of the T315I mutant of AbI kinase.
Chem Biol Drug Des. 2007 Sep;70(3):171-81. doi: 10.1111/j.1747-0285.2007.00556.x.
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Rational design of inhibitors that bind to inactive kinase conformations.
Nat Chem Biol. 2006 Jul;2(7):358-64. doi: 10.1038/nchembio799.
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Allosteric inhibitors of Bcr-abl-dependent cell proliferation.
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Characterization of AMN107, a selective inhibitor of native and mutant Bcr-Abl.
Cancer Cell. 2005 Feb;7(2):129-41. doi: 10.1016/j.ccr.2005.01.007.
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Science. 2004 Jul 16;305(5682):399-401. doi: 10.1126/science.1099480.
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Science. 2001 Aug 3;293(5531):876-80. doi: 10.1126/science.1062538. Epub 2001 Jun 21.

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