Vukmir Rade B
Critical Care Medicine Associates, Sewicley, PA 15143, U.S.A. Department of Emergency Medicine, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, U.S.A.
Clin Med Cardiol. 2009 Feb 9;3:9-14. doi: 10.4137/cmc.s695.
This study attempted to correlate the initial cardiac rhythm and survival from prehospital cardiac arrest, as a secondary end-point.
Prospective, randomized, double-blinded clinical intervention trial where bicarbonate was administered to 874 prehospital cardiopulmonary arrest patients in prehospital urban, suburban, and rural emergency medical service environments.
This group's manifested an overall survival rate of 13.9% (110 of 793) of prehospital cardiac arrest patients. The most common presenting arrhythmia was ventricular fibrillation (VF) (45.0%), asystole (ASY) (34.4%), and pulseless electrical activity (PEA) (15.7%). Less commonly found were normal sinus rhythm (NSR) (1.8%), other (1.8%), ventricular tachycardia (VT) (0.6%), and atrioventricular block (AVB) (0.5%) as prearrest rhythms. The best survival was noted in those with a presenting rhythm of AVB (57.1%), VT (33.3%), VF (15.7%), NSR (14.3%), PEA (11.2%), and ASY (11.1%) (p = 0.02). However, there was no correlation between the final cardiac rhythm and outcome, other than an obvious end-of-life rhythm.
The most common presenting arrhythmia was VF (45%), while survival is greatest in those presenting with AVB (57.1%).
本研究试图将院外心脏骤停后的初始心律与生存率相关联,作为次要终点。
前瞻性、随机、双盲临床干预试验,在城市、郊区和农村的院外急救医疗服务环境中,对874例院外心脏骤停患者给予碳酸氢盐治疗。
该组院外心脏骤停患者的总体生存率为13.9%(793例中的110例)。最常见的初始心律失常为室颤(VF)(45.0%)、心脏停搏(ASY)(34.4%)和无脉电活动(PEA)(15.7%)。较少见的心脏骤停前心律为正常窦性心律(NSR)(1.8%)、其他(1.8%)、室性心动过速(VT)(0.6%)和房室传导阻滞(AVB)(0.5%)。观察到初始心律为AVB的患者生存率最高(57.1%), VT为(33.3%), VF为(15.7%), NSR为(14.3%), PEA为(11.2%), ASY为(11.1%)(p = 0.02)。然而,除明显的临终心律外,最终心律与预后之间无相关性。
最常见的初始心律失常为VF(45%),而初始心律为AVB的患者生存率最高(57.1%)。