Department of Anesthesiology and Pain Medicine, College of Medicine, Chung-Ang University, Seoul, Korea.
Korean J Anesthesiol. 2010 Apr;58(4):409-12. doi: 10.4097/kjae.2010.58.4.409. Epub 2010 Apr 26.
A 23-year-old woman with MELAS (mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes) underwent a laparoscopy-assisted appendectomy. MELAS syndrome is a multisystemic disease caused by mitochondrial dysfunction. General anesthesia has several potential hazards to patients with MELAS syndrome, such as malignant hyperthermia, hypothermia, and metabolic acidosis. In this case, anesthesia was performed with propofol, remifentanil TCI, and atracurium without any surgical or anesthetic complications. We discuss the anesthetic effects of MELAS syndrome.
一位 23 岁的女性患有 MELAS(线粒体肌病、脑病、乳酸酸中毒和卒中样发作),接受了腹腔镜辅助阑尾切除术。MELAS 综合征是一种由线粒体功能障碍引起的多系统疾病。全身麻醉对 MELAS 综合征患者有几种潜在的危险,如恶性高热、低体温和代谢性酸中毒。在这种情况下,使用丙泊酚、瑞芬太尼 TCI 和阿曲库铵进行麻醉,没有任何手术或麻醉并发症。我们讨论了 MELAS 综合征的麻醉效果。