一名55岁男性在开始使用阿立哌唑后出现首次躁狂发作。
First manic episode in a 55-year-old man after initiation of aripiprazole.
作者信息
Donohue Andrew
机构信息
Dr. Donohue is a Forensic Psychiatrist, Delaware Psychiatric Center, New Castle, Delaware.
出版信息
Psychiatry (Edgmont). 2010 Apr;7(4):37-9.
Abstract
Aripiprazole is a novel antipsychotic medication that is used to treat a number of psychiatric conditions, including schizophrenia, bipolar disorder, and major depressive disorder. Although not specifically indicated for this, novel antipsychotics including aripiprazole are also used for treatment of obsessive compulsive disorder. The following case involves a 55-year-old man with refractory obsessive compulsive disorder who developed his first manic episode after taking aripiprazole. The author reviews other cases of aripiprazole-induced mania and discusses the possible pharmacodynamic mechanisms of this reaction.
摘要
阿立哌唑是一种新型抗精神病药物，用于治疗多种精神疾病，包括精神分裂症、双相情感障碍和重度抑郁症。虽然未专门针对此症，但包括阿立哌唑在内的新型抗精神病药物也用于治疗强迫症。以下病例涉及一名55岁患有难治性强迫症的男性，他在服用阿立哌唑后首次出现躁狂发作。作者回顾了其他阿立哌唑诱发躁狂的病例，并讨论了这种反应可能的药效学机制。
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