Patil Sumangala M, Chaudhuri Dipayan, Dhanakshirur Gopal B
Department of Physiology, B.L.D.E.A.'s Shri B.M. Patil Medical College, Bijapur - 586 103.
Indian J Physiol Pharmacol. 2009 Oct-Dec;53(4):375-9.
Exercise increases oxygen consumption and causes a disturbance of intracellular pro-oxidant-antioxidant homeostasis. Athletes are exposed to acute and chronic stress that may lead to increased generation of oxidative species. Hence oxidative stress increases in athletes. Administration of antioxidant like alpha-tocopherol as supplementation may reduce the cell damage caused due to oxidative stress. In the present study, our aim was to study the effects of alpha-tocopherol supplementation on the cardiopulmonary fitness in endurance athletes (cyclists) and non-athletes. Our study included 40 cyclists who were trained under District Youth Service & Sports Office. 40 controls were randomly selected from student group of B.L.D.E.A's Medical College. Alpha-tocopherol (Vitamin E) 200 mg/day for 21 days wasgiven to study group and placebo was given to placebo group. Various physiological parameters like heart rate, blood pressure, respiratory rate were recorded, for assessing cardiopulmonary fitness: Physical Fitness Index (PFI) and VO2 max ml/min/kg were recorded before and after supplementation of vitamin E in athletes, and were compared with placebo group before and after supplementation of placebo and also with non-athletes. The results obtained from present study indicate that antioxidant like alpha-tocopherol supplementation did not contribute significantly to improve the cardiopulmonary fitness of endurance athletes.
运动增加氧气消耗,并导致细胞内促氧化剂-抗氧化剂稳态的紊乱。运动员暴露于急性和慢性应激之下,这可能导致氧化物质生成增加。因此,运动员体内的氧化应激会增加。补充抗氧化剂如α-生育酚可能会减少氧化应激引起的细胞损伤。在本研究中,我们的目的是研究补充α-生育酚对耐力运动员(自行车运动员)和非运动员心肺适能的影响。我们的研究包括40名在地区青年服务与体育局训练的自行车运动员。40名对照者从B.L.D.E.A医学院的学生群体中随机选取。研究组给予200毫克/天的α-生育酚(维生素E),为期21天,安慰剂组给予安慰剂。记录心率、血压、呼吸频率等各种生理参数,以评估心肺适能:在运动员补充维生素E之前和之后记录体能指数(PFI)和最大摄氧量(VO2 max)毫升/分钟/千克,并与安慰剂组补充安慰剂之前和之后以及非运动员进行比较。本研究获得的结果表明,补充抗氧化剂如α-生育酚对改善耐力运动员的心肺适能没有显著作用。