Schonfeld Steven E
J Calif Dent Assoc. 2010 Apr;38(4):272-83.
Most of the tissue destruction in periodontal disease is caused by the patient's inflammatory response. Classical approaches to controlling inflammation rely on attempts to eliminate pathogenic bacteria that incite the inflammatory response through mechanical or chemical means. This approach still has a place in treating periodontal inflammation today. Emerging and future approaches will rely more on modifying the inflammatory response itself, by limiting the activity of proinflammatory pathways and by amplifying pathways that resolve inflammation.
牙周病中的大多数组织破坏是由患者的炎症反应引起的。控制炎症的传统方法依赖于试图通过机械或化学手段消除引发炎症反应的致病细菌。如今，这种方法在治疗牙周炎症方面仍有一席之地。新兴的和未来的方法将更多地依赖于通过限制促炎途径的活性以及增强炎症消退途径来调节炎症反应本身。
