Seton Brain and Spine Institute, Austin, Texas, USA.
J Neurosurg. 2010 Nov;113(5):1112-4. doi: 10.3171/2010.5.JNS091931. Epub 2010 May 28.
The authors report the case of intracranial neuritis ossificans presenting as chronic accessory neuropathy. Neuritis ossificans is a rare reactive nerve disease that has been reported to affect systemic peripheral nerves. To the best of the authors' knowledge, this is the first documented case of neuritis ossificans observed in a cranial nerve. The lesion was revealed on imaging studies and appeared, intraoperatively, as a nonsessile intradural lesion with significant calcification of rootlets of the lower cranial nerves. Microscopically, the lesion featured zonal heterotopic calcification typical of neuritis ossificans. Although it is a rare entity, neuritis ossificans can be considered in the differential diagnosis of lower cranial nerve neuropathy.
作者报告了一例以慢性副神经病为表现的颅内神经炎骨化病例。神经炎骨化是一种罕见的反应性神经疾病，据报道可影响全身周围神经。据作者所知，这是首例在颅神经中观察到的神经炎骨化病例。病变在影像学研究中显示，术中表现为无蒂硬脊膜内病变，伴有颅神经下根明显钙化。显微镜下，病变具有典型的神经炎症骨化的带状异位钙化。虽然它是一种罕见的实体，但在鉴别诊断颅神经神经病时可以考虑神经炎骨化。
